TOBACCO: PRENATAL EFFECTS AND ADOLESCENT USE

描述：（申请人摘要） 产妇保健做法和儿童发展项目是一个前景广阔的项目， 产前烟草暴露对755名孕妇子代影响的研究 妇女 我们已经确定了产前烟草暴露的显著影响， 对后代中枢神经系统发育的影响， 犯罪行为和同伴问题。 10岁时，孩子们 已经开始用烟草和其他物质做实验。 这些孩子 他们更沮丧和焦虑，他们有更多的注意力问题， 侵略和犯罪 我们将评估心理和身体发育的长期影响， 气质，心理状态，活动水平，学习成绩， 行为问题、环境和产前暴露 14岁和16岁青少年药物使用情况以及 14至16岁之间的烟草使用。 以前的研究都无法 探索青少年烟草使用的预测因素，从出生到 青春期 该队列是低收入妇女的一般人口样本，选自 产前诊所 一半是白人，一半是非裔美国人。 我们在产前4个月对这些母亲和她们的孩子进行了评估， 7、分娩、8和18个月、3、6和10年。 我们有一个特殊的 10年随访率为91%。

DESCRIPTION: (Applicant's Abstract) The Maternal Health Practices and Child Development Project is a prospective study of the effects of prenatal tobacco exposure on the offspring of 755 women. We have identified significant effects of prenatal tobacco exposure on the offsprings' development of the central nervous system and on delinquent behavior and peer problems. At 10 years of age, the children have begun to experiment with tobacco and other substances. These children were more depressed and anxious, they had more attention problems, aggression, and delinquency. We will assess the long-term effects of mental and physical development, temperament, psychological status, activity levels, academic performance, behavior problems, the environment, and prenatal exposure on the adolescents' substance use at age 14 and 16 and on the development of tobacco use between the ages of 14 and 16. No prior study has been able to explore the predictors of adolescent tobacco use across time, from birth to adolescence. The cohort is a general population sample of low income women selected from a prenatal clinic. Half the women are Caucasian, half are African-American. We have assessed these mothers and their children at prenatal months 4 and 7, delivery, 8 and 18 months, 3, 6, and 10 years. We have an exceptional follow-up rate of 91% at 10 years.