Palaeo-population genomics: studying adaptation using ancient human DNA

古种群基因组学：利用古代人类 DNA 研究适应

• 批准号: DE180100883
• 负责人: Dr Christian Huber
• 金额: $ 24.2万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-05-04 至 2021-04-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE180100883
• 关键词: Palaeo; population; genomics; studying; adaptation

This project aims to apply state-of-the-art population and quantitative genetic techniques to a powerful new database of ancient human genomes - spanning from hunter gatherers and early farmers through to the Middle Ages. This will be used to build the first detailed portrait of human genetic adaptation through time. This record will capture the major socio-cultural transitions in human history, and reveal the genetic and environmental drivers that have shaped modern human genetic diversity and pathology.

该项目旨在将最先进的人口和定量遗传技术应用于一个强大的古人类基因组新数据库-从狩猎采集者和早期农民到中世纪。这将被用来建立第一个详细的人类遗传适应随着时间的推移。该记录将捕捉人类历史上主要的社会文化转变，并揭示塑造现代人类遗传多样性和病理学的遗传和环境驱动因素。