VALDICHRO a software tool for validation of circular dichroism spectroscopic data and bioprocess quality analyses
VALDICHRO a software tool for validation of circular dichroism spectroscopic data and bioprocess quality analyses
批准号:
BB/G023476/1
负责人:
Bonnie Wallace
金额:
$14.85万
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2009
资助国家:
英国
项目状态:
已结题
起止时间:
2009 至 --
中文摘要
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英文摘要
The method of circular dichroism (CD) spectroscopy is widely used in studies of proteins to examine their structure, interactions and folding. It is also used by industry as a means of checking quality and consistency of proteins produced as pharmaceuticals. This project is to develop new software, VALIDICHRO, as a tool/resource for assessing the quality of CD data, as a standards test of research good practice, in bioprocessing quality control, and as a validation method for data generated that will be shared publicly in the Protein Circular Dichroism Data Bank repository.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
DOI:
10.7554/elife.58593
发表时间:
2020-10-22
期刊:
eLife
影响因子:
7.7
作者:
[Sait LG, Sula A, Ghovanloo MR, Hollingworth D, Ruben PC, Wallace BA]
通讯作者:
Wallace BA
Structure/Function Drug Interaction Studies on Voltage-Gated Sodium Channels
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批准号:BB/V018035/1
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项目类别:Research Grant
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资助金额:$3.9万
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财政年份:2022
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负责人:Bonnie Wallace
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依托单位:
Binding and interactions of Brazilian toxins to voltage-gated sodium channels: The Rational Search for New Drugs
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批准号:BB/T01153X/1
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项目类别:Research Grant
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资助金额:$2.03万
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财政年份:2020
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负责人:Bonnie Wallace
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依托单位:
Bioinformatics Resources for Circular Dichroism Spectroscopy and Structural Biology: Operation, Enhancement, Curation, and New Developments
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批准号:BB/P024092/1
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项目类别:Research Grant
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资助金额:$93.79万
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财政年份:2018
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负责人:Bonnie Wallace
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依托单位:
Structure and Function of the Human 1.8 Voltage-Gated Sodium Channel Associated with Pain Sensation
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批准号:BB/R001294/1
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项目类别:Research Grant
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资助金额:$73.99万
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财政年份:2017
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负责人:Bonnie Wallace
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依托单位:
Biophysical studies of the structure/function of antimicrobial peptides and enzymes isolated from extremophile organisms
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批准号:BB/N012763/1
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项目类别:Research Grant
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资助金额:$4.51万
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财政年份:2016
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负责人:Bonnie Wallace
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依托单位:
UK-US Collaboration on Structure, Function and Dynamics of Voltage-Gated Sodium Channels
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批准号:BB/L026252/1
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项目类别:Research Grant
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资助金额:$5.46万
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财政年份:2014
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负责人:Bonnie Wallace
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依托单位:
Structure and Function of Voltage-Gated Ion Channels and their Applications for Rational Drug Design
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批准号:BB/L006790/1
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项目类别:Research Grant
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资助金额:$67.84万
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财政年份:2014
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负责人:Bonnie Wallace
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依托单位:
The Protein Circular Dichroism Data Bank, the DichroWeb Server, and ValiDichro: Data Sharing, Analysis and Standards Resources for CD Spectroscopy
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批准号:BB/J019135/1
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项目类别:Research Grant
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资助金额:$87.31万
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财政年份:2013
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负责人:Bonnie Wallace
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依托单位:
UK/Taiwan Interchange on Synchrotron Radiation Circular Dichroism Spectroscopy
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批准号:BB/L004976/1
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项目类别:Research Grant
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资助金额:$1.58万
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财政年份:2013
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负责人:Bonnie Wallace
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依托单位:
Powder Diffraction Methods for Membrane Protein Structure Determination
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批准号:BB/J020702/1
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项目类别:Research Grant
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资助金额:$14.95万
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财政年份:2012
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负责人:Bonnie Wallace
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依托单位:
An International UK-Brazil Collaboration using Synchrotron Radiation Circular Dichroism Spectroscopy to Study Protein Structure and Function
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批准号:BB/J019747/1
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项目类别:Research Grant
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资助金额:$3.49万
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财政年份:2012
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负责人:Bonnie Wallace
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依托单位:
Developing Oriented Circular Dichroism Spectroscopy as a Methodological Tool for Characterising Membrane Proteins
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批准号:BB/H023852/1
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项目类别:Research Grant
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资助金额:$15.4万
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财政年份:2011
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负责人:Bonnie Wallace
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依托单位:
Crystal structure analysis of a voltage-gated sodium channel
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批准号:BB/H01070X/1
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项目类别:Research Grant
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资助金额:$65.4万
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财政年份:2010
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负责人:Bonnie Wallace
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依托单位:
Parallel electrophysiological characterization of sodium channels
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批准号:EP/H043888/1
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项目类别:Research Grant
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资助金额:$60.97万
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财政年份:2010
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负责人:Bonnie Wallace
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依托单位:
Developing Synchrotron Radiation Circular Dichroism (SRCD) Spectroscopy Methods and Applications for Structural Biology
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批准号:BB/G530417/1
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项目类别:Research Grant
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资助金额:$5.71万
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财政年份:2009
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负责人:Bonnie Wallace
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依托单位:
Support for the Protein Circular Dichroism Data Bank and the Dichroweb Analysis Server
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批准号:BB/F010346/1
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项目类别:Research Grant
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资助金额:$54.86万
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财政年份:2008
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负责人:Bonnie Wallace
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依托单位:
Analyses of aphid sodium channels and prediction of pesticide interactions
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批准号:BB/F009143/1
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项目类别:Research Grant
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资助金额:$12.83万
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财政年份:2008
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负责人:Bonnie Wallace
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依托单位:
Fold recognition by synchrotron radiation circular dichroism spectroscopy: a new tool for structural proteomics and structural molecular biology
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批准号:BB/D008581/1
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项目类别:Research Grant
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资助金额:$34.47万
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财政年份:2006
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负责人:Bonnie Wallace
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依托单位:
Gramicidin/Lipid Co-Crystals
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批准号:8816981
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项目类别:Continuing Grant
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资助金额:$31.5万
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财政年份:1989
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负责人:Bonnie Wallace
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依托单位:
The Structure of Gramicidin, a Transmembrane Channel
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批准号:8517866
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项目类别:Standard Grant
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资助金额:$0.23万
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财政年份:1986
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负责人:Bonnie Wallace
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依托单位:
国内基金
海外基金
低辐射空间环境下商用多核处理器层次化软件容错技术研究
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批准号:90818016
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项目类别:重大研究计划
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资助金额:50.0万元
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批准年份:2008
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负责人:傅忠传
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依托单位: