Annexin1-mediated calcium signalling controls plant responses to ozone

膜联蛋白1介导的钙信号传导控制植物对臭氧的反应

• 批准号: BB/K009869/1
• 负责人: Julia Davies
• 金额: $ 51.09万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FK009869%2F1
• 关键词: Annexin1; mediated; calcium; signalling; controls

Levels of ozone as a ground-level pollutant threaten crop and pasture productivity. European crop losses are worth several billion Euros annually. The frequency of ozone "episodes" (when local conditions promote significant ozone elevation during the growing season) is set to increase. Ozone reduces shoot (and root) growth, causes leaf loss and affects grain development. Ozone can also exacerbate the effects of drought on plants. With drought affecting large areas of the UK, how plants defend against ozone must be understood to combat this problem. Plants respond to ozone by generating an internal signal that causes changes in the genes that are expressed. It can also lead to cell death. An increase in calcium is an important component of this signal. We have discovered a mutant plant that cannot generate this calcium signal. By comparing the mutant with its non-mutated wild type, we can use the mutant as a tool with which to reveal the changes that occur in response to ozone from the genetic to whole plant level. We know the protein that is missing in the mutant and will test for its function in critical types of cell. We will also assess its importance to a plant's ability to regulate its water and gas relations and grow under ozone stress alone or combined with drought. These comparative studies will also identify genes likely to be of use in breeding programmes for ozone-resistant crops.

臭氧水平作为一种地面污染物威胁作物和牧场的生产力。欧洲农作物每年损失数十亿欧元。臭氧“插曲”（当地条件促使生长季节臭氧显著升高）的频率将会增加。臭氧减少茎（和根）的生长，造成叶片损失，影响谷物发育。臭氧还会加剧干旱对植物的影响。随着干旱影响英国大片地区，必须了解植物如何抵御臭氧来解决这个问题。植物对臭氧的反应是产生一种内部信号，导致表达的基因发生变化。它也会导致细胞死亡。钙含量的增加是这一信号的重要组成部分。我们发现一种突变植物不能产生这种钙信号。通过将突变体与未突变的野生型进行比较，我们可以利用突变体作为一种工具，揭示从遗传到整个植物水平上对臭氧的反应所发生的变化。我们知道突变体中缺失的蛋白质，并将测试其在关键类型细胞中的功能。我们还将评估它对植物调节水和气关系的能力的重要性，以及在臭氧胁迫单独或与干旱结合的情况下生长的能力。这些比较研究还将确定可能用于抗臭氧作物育种计划的基因。

项目成果

ANNEXIN1 mediates calcium-dependent systemic defense in Arabidopsis plants upon herbivory and wounding.

ANNEXIN1 介导拟南芥植物在食草和受伤时的钙依赖性系统防御。

• DOI: 10.17863/cam.70718
• 发表时间: 2021
• 作者: Malabarba J

ANNEXIN1 mediates calcium-dependent systemic defense in Arabidopsis plants upon herbivory and wounding

• DOI: 10.1111/nph.17277
• 发表时间: 2021-03-19
• 期刊: NEW PHYTOLOGIST
• 影响因子: 9.4
• 作者: Malabarba, Jaiana;Meents, Anja K.;Mithoefer, Axel
• 通讯作者: Mithoefer, Axel

Damage Signaling by Extracellular Nucleotides: A Role for Cyclic Nucleotides in Elevating Cytosolic Free Calcium?

• DOI: 10.3389/fpls.2021.788514
• 发表时间: 2021
• 期刊: Frontiers in plant science
• 影响因子: 5.6
• 作者: Sun J;Ning Y;Wang L;Wilkins KA;Davies JM
• 通讯作者: Davies JM

Calcium-Mediated Abiotic Stress Signaling in Roots.

根部钙介导的非生物应激信号。

• DOI: 10.17863/cam.4839
• 发表时间: 2016
• 作者: Wilkins K