Cell circuitry for metals: Integrative metabolism for cobalt uptake and cobalamin production

金属的细胞电路：钴吸收和钴胺素生成的综合代谢

• 批准号: BB/L009226/1
• 负责人: Nigel Robinson
• 金额: $ 42.01万
• 依托单位: Durham University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FL009226%2F1
• 关键词: Cell; circuitry; metals; Integrative; metabolism

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前，GtR 中尚未提供所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但可能是因为它包含个人详细信息等敏感信息。

项目成果

A tight tunable range for Ni(II) sensing and buffering in cells.

• DOI: 10.1038/nchembio.2310
• 发表时间: 2017-04
• 期刊: Nature chemical biology
• 影响因子: 14.8
• 作者: Foster AW;Pernil R;Patterson CJ;Scott AJP;Pålsson LO;Pal R;Cummins I;Chivers PT;Pohl E;Robinson NJ
• 通讯作者: Robinson NJ

An XAS investigation of the nickel site structure in the transcriptional regulator InrS.

• DOI: 10.1016/j.jinorgbio.2017.08.003
• 发表时间: 2017-12
• 期刊: Journal of inorganic biochemistry
• 影响因子: 3.9
• 作者: Carr CE;Foster AW;Maroney MJ
• 通讯作者: Maroney MJ

Trans-oligomerization of duplicated aminoacyl-tRNA synthetases maintains genetic code fidelity under stress.

• DOI: 10.1093/nar/gkv1020
• 发表时间: 2015-11-16
• 期刊: Nucleic acids research
• 影响因子: 14.9
• 作者: Rubio MÁ;Napolitano M;Ochoa de Alda JA;Santamaría-Gómez J;Patterson CJ;Foster AW;Bru-Martínez R;Robinson NJ;Luque I
• 通讯作者: Luque I

Finding the right match

寻找合适的匹配

• DOI: 10.1038/s41570-019-0083-5
• 发表时间: 2019
• 期刊: Nature Reviews Chemistry
• 影响因子: 36.3
• 作者: Schilter D

Fine control of metal concentrations is necessary for cells to discern zinc from cobalt.

• DOI: 10.1038/s41467-017-02085-z
• 发表时间: 2017-12-01
• 期刊: Nature communications
• 影响因子: 16.6
• 作者: Osman D;Foster AW;Chen J;Svedaite K;Steed JW;Lurie-Luke E;Huggins TG;Robinson NJ
• 通讯作者: Robinson NJ