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Multi-Allergen Screening Technology (MAST)

Multi-Allergen Screening Technology (MAST)
多重过敏原筛查技术 (MAST)
批准号:
EP/H029591/1
负责人:
Andrew Shaw
金额:
$14.82万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2010
资助国家:
英国
项目状态:
已结题
起止时间:
2010 至 --

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中文摘要
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英文摘要
We have been working on new technology that will ultimately allow up to 100 tests to be performed on blood without the need to prepare the sample in any way. The first target for the MAST platform will be to screen for allergy. The allergic response occurs when the concentrations of an antibody in the blood reach trigger level and then symptoms of runny nose begin to show. However, concentration much 10,000 times greater than the trigger level can cause a fatal anaphylactic shock. Allergy is on the increase in western cultures although it remains fairly rare on the African continent. What is causing this rise? Some 60 million Americans suffer from some airborne allergy but 11 million have serious, life-threatening food allergies. The technology will allow a simple blood test to be performed at the GP to screen for the top 10, 20 or 100 allergies and give an answer to the patient in 8 minutes. From this profile of allergy we will soon be able to discover whether allergies are related and how they work together to form an extreme response. The technology if successful will cost 5K for each GP surgery and approximately 30 per test. The objective of the current research is to take the instrument in the laboratory and make it ready for a full clinical validation.
期刊论文(7)
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科研奖励(0)
会议论文
Differential immuno-kinetic assays of allergen-specific binding for peanut allergy serum analysis.
用于花生过敏血清分析的过敏原特异性结合的差异免疫动力学测定。
DOI: 10.1007/s00216-012-6390-z
发表时间: 2012
期刊: Analytical and bioanalytical chemistry
影响因子: 4.3
作者: [Olkhov RV]
通讯作者: Olkhov RV
DOI: 10.1016/j.bios.2012.04.023
发表时间: 2012-06
期刊: Biosensors & bioelectronics
影响因子: 12.6
作者: [R. Olkhov;Robert J. Parker;A. M. Shaw]
通讯作者: R. Olkhov;Robert J. Parker;A. M. Shaw
Measurement of the localised plasmon penetration depth for gold nanoparticles using a non-invasive bio-stacking method.
使用非侵入性生物堆积方法测量金纳米粒子的局部等离子体穿透深度。
DOI: 10.1039/c3cp50758k
发表时间: 2013
期刊: PCCP
影响因子: --
作者: [Read T]
通讯作者: Read T
Human serum albumin interference on plasmon-based immunokinetic assay for antibody screening in model blood sera.
人血清白蛋白对基于等离子体的免疫动力学测定的干扰,用于模型血清中抗体筛选。
DOI: 10.1016/j.ab.2010.05.015
发表时间: 2010
期刊: Analytical biochemistry
影响因子: 2.9
作者: [Van Vuuren BJ]
通讯作者: Van Vuuren BJ
Upgrading woody biomass to biocoal using a novel microwave induced plasma technology
  • 批准号:
    EP/P51035X/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $6.96万
  • 财政年份:
    2016
  • 负责人:
    Andrew Shaw
  • 依托单位:
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