FUNCTIONAL ORGANIZATION OF THE SOMATOSENSORY SYSTEM

六类解剖和电生理实验是 提出了关于常态组织、常态发展的建议 组织，以及损伤对正常组织和 猴的体感系统的发展。(1)微电极 测绘程序和解剖示踪剂将用于进一步确定 躯体感觉皮层和丘脑的细分、相互联系 细分，以及内在联系的区域模式。(2)单身人士 单元录音，在某种程度上，多单元录音将用于 确定神经元中不同的皮质小体表示有何不同 响应类型，以及高密度的单一单元“映射”将被用于 确定神经元响应类型在一个场中的分布情况，以及 神经元反应类型的“模块化”分组发生。(3)数量有限 将探索马达和马达的组织和联系 使用微刺激标测程序的运动前区域，以及解剖学 追踪器。(4)实验将开始使用解剖示踪剂和 微电极标测研究大鼠的正常发育 体感系统。(5)周围神经损伤的影响； 中枢神经系统损伤对脑组织正常组织的影响 将用微电极研究成年哺乳动物的体感系统 测绘程序。(6)平行实验将比较 周围神经损伤与中枢神经感觉系统的组织 在新生儿和幼年动物中发现的神经系统损伤 成年人。

Six categories of anatomical and electrophysiological experiments are proposed on the normal organization, the development of normal organization, and the effects of injury on normal organization and development of the somatosensory system of monkeys. (1) Microelectrode mapping procedure and anatomical tracers will be used to determine further subdivisions of the somatosensory cortex and thalamus, the interconnections of subdivisions, and areal patterns of intrinsic connections. (2) Single unit recordings and, to some extent, multi-unit recordings will be used to determine how separate cortical body representations differ in neuron response types, and high density single unit "mapping" will be used to determine how neuron response types are distributed within a field, and if "modular" grouping of neuron response types occurs. (3) A limited number of experiments will explore the organization and connections of motor and premotor fields using microstimulation mapping procedures, and anatomical tracers. (4) Experiments will start using anatomical tracers and microelectrode mapping to investigate the normal development of the somatosensory system. (5) The effects of peripheral nerve injury, and central nervous system damage on altering the normal organization of the somatosensory system in adult mammals will be studied with microelectrode mapping procedures. (6) Parallel experiments will compare the effects on somatosensory system organization of peripheral nerve injury and central nervous system damage in newborn and young animals with those found in adults.