STATISTICAL ANALYSIS OF PEDIATRIC TASK FORCE DATA BASE

高血压是一个公认的心血管疾病的危险因素 在成年人中。此外，许多研究表明， 纵向儿童血压测定。一个重要 儿童高血压研究中尚未解决的目标是确定 小儿血压水平是一个孩子在成人的风险增加 高血压有两个NHLBI工作组在血压 儿童控制，1977年和1987年发表了报告。之一 每个工作组的目标都是确定适当的任务， 儿童血压。在第二次工作队报告中， 九项大型流行病学研究被合并到一个数据库中， 超过70，000个读数，从中得出血压数据， 年龄和性别的函数。然而，许多研究工作者表示， 身高与血压的关系比年龄更密切， 儿童血压的标准数据应按身高划分 而不是年龄。此应用程序的一个重要目标是定义 性别特异性血压波动是年龄和 高度 高血压研究中另一个尚未解决的问题是确定高血压的精确 不同种族人群血压分布的年龄 分歧这是为数不多的可以解决这个问题的数据库之一 因为我们有超过43,000名白色儿童的读数， 4,500名西班牙裔儿童。这将是一个绰绰有余 样本量来检验这个假设。如果发现差异， 估计种族差异的最早年龄是非常有趣的， 在血压上是显而易见的。 总之，以前的儿科工作组报告仅限于 所列数据的范围，主要是由于篇幅的限制。我们将 构建血压曲线图，它是年龄，性别，种族， 和身高，这应该提供一个更全面的儿科概况， 血压分布比以前发表的任何工作。

Hypertension is a well-recognized risk factor for cardiovascular disease in adults. Furthermore, many studies have shown that there is tracking among longitudinal pediatric blood pressure determinations. An important unresolved goal in pediatric hypertension research is to define at what level of pediatric blood pressure is a child at increased risk for adult hypertension. There have been two NHLBI Task Forces in Blood Pressure Control in Children which have published reports in 1977 and 1987. One of the goals of each task force has been to define appropriate percentiles for blood pressure in children. In the Second Task Force Report, results from nine large epidemiologic studies were combined into a data base with more than 70,000 readings from which blood pressure percentiles were derived as a function of age and sex. However, many research workers have stated that height is more strongly related to blood pressure than age and have urged that Normative data for pediatric blood pressure be demarcated by height rather than age. An important goal of this application is to define sex-specific blood pressure percentiles that are a function of both age and height. Another unresolved issue in hypertension research is to define the precise age at which blood pressure distributions for different racial groups diverge. This is one of the few data bases that can address this issue since we have readings from over 43,000 white children, 23,000 black children, and 4,500 hispanic children. This will be a more than adequate sample size to test this hypothesis. If differences are found, than it is of great interest to estimate the earliest age at which racial differences in blood pressure are apparent. In summary, the previous Pediatric Task Force reports have been limited in the scope of data presented, mainly due to space limitations. We will construct blood pressure percentiles that are a function of age, sex, race, and height, which should provide a more comprehensive profile of pediatric blood pressure distributions than any previously published work.