EFFECT OF TEMPERATURE ON PRETERM INFANT SLEEP-WAKE STATE

温度对早产儿睡眠觉醒状态的影响

• 批准号: 3476463
• 负责人: KAREN A. THOMAS
• 金额: $ 9.79万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-06-01 至 1995-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3476463
• 关键词: behavior test; body temperature regulation; circadian rhythms; home health care; hospital patient care; human subject; neonatal intensive care; nurses; nursing; nursing intervention; patient monitoring device; pediatric nursing; personal computers; premature infant human; sleep; temperature; thermometry

One of the many challenges facing the preterm infant is synchronizing activities with the normal, 24-hour day. There is convincing evidence linking the day-night patterns of body temperature and sleep-wake activity in adults however, little is known of this relationship in preterm infants. Preterm infants, because of their thermoregulatory limitations, require heating by incubators or other clinical devices. There has been little investigation of how such heating may alter sleep-wake pattern. This relationship is significant to the preterm infant's adaptation to the 24- hour day-night pattern. Infant rhythmicity and the ability to synchronize with caregiving patterns are factors salient to infant-parent interaction. Nursing management of incubators, based on recognition of the preterm infant's developing body temperature biorhythm, is a potential intervention for promoting sleep-wake pattern. The purpose of this research is to examine the relationship between temperature and sleep-wake state in preterm and term gestation infants. Specific aims of the study are to examine the development of temperature biorhythm in hospitalized infants born prematurely, determine the relationship between preterm infant sleep- wake state and both infant body and incubator temperature, and to compare body temperature biorhythm and sleep-wake state and both infant body and incubator temperature, and to compare body temperature biorhythm and sleep- wake patterns in preterm and term infants in the home environment. Preterm infants will be studied longitudinally and cross-sectionally using an intensive within subject design. Incubator temperature and infant abdominal skin temperature will be recorded during a 24-hour period using a computerized data acquisition system while infant state will be determined by lapse-time video recording. Following discharge, preterm infants and a comparison group of term infants will studied in the home environment where infant abdominal skin temperature (Vitalog) and infant sleep-wake state will be measured. Cyclicity in both body temperature and sleep-wake states will be determined using power spectral analysis. Comparisons of preterm infants across time and cross-sectionally will reveal developmental changes in biorhythm of body temperature and sleep-awake states. The effect of premature birth on the development of temperature and sleep-wake state patterns will be evidenced in comparisons of term and preterm infants.

早产儿面临的众多挑战之一是同步 正常的24小时活动。 有令人信服的证据 将体温的昼夜模式和睡眠-觉醒活动联系起来 然而，对于成年人来说，人们对早产儿的这种关系知之甚少。 早产儿，因为他们的体温调节限制，需要 通过培养箱或其他临床设备加热。 几乎没有 研究这种加热如何改变睡眠-觉醒模式。 这 早产儿对24小时睡眠的适应有重要意义。 小时昼夜模式。 婴儿的节律性和同步能力 婴儿-父母互动的显著因素是婴儿-父母互动的显著因素。 基于早产儿识别的保育箱护理管理 婴儿发育中的体温生物节律，是一种潜在的干预措施 促进睡眠模式。 本研究的目的是 研究温度和睡眠-觉醒状态之间的关系， 早产儿和足月妊娠婴儿。 研究的具体目标是 检查住院婴儿体温生物节律的发展 早产儿，决定早产儿睡眠的关系， 唤醒状态和婴儿身体和保温箱温度，并比较 体温生物节律和睡眠-觉醒状态以及婴儿身体和 恒温箱温度，并比较体温生物节律和睡眠- 在家庭环境中早产儿和足月儿的唤醒模式。 早产 婴儿将进行纵向和横断面研究，使用 在主题设计中强化。 培养箱温度和婴儿 在24小时内，使用 计算机化数据采集系统，同时确定婴儿状态 通过延时录像 出院后，早产儿和 对照组的足月婴儿将在家庭环境中进行研究， 婴儿腹部皮温与婴儿睡眠-觉醒状态 将被衡量。 体温和睡眠-觉醒状态的周期性 将使用功率谱分析来确定。 早产儿比较 婴儿在不同时间和不同区域的发育变化 体温和睡眠-清醒状态的生物节律。 的影响 早产对体温和睡眠-觉醒状态的影响 将在足月儿和早产儿的比较中证明模式。