PLASMA ENHANCED PARYLENE COATINGS FOR IMPLANTED ELECTRON
PLASMA ENHANCED PARYLENE COATINGS FOR IMPLANTED ELECTRON
批准号:
3504624
负责人:
IH-HOUNG LOH
金额:
$5.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-12-15 至 1992-06-14
中文摘要
阻碍发展的一些最重要的问题
用于神经残疾的可植入神经假体包括
植入器械的长期绝缘和保护。 具体地说,
微机械薄膜记录和刺激微电极探针
以及将这些电极与一个电源连接的微型电线或电缆,
控制和权力必须受到保护,从敌对的离子环境,
细胞外液几十年,如果他们要可靠地用于人类。
本研究的长期目标是开发生物相容性涂层
系统将允许这些 神经假体植入物的功能
在植入物接受者的生命周期内可靠地进行。
目前最有前途的涂层保护的结合面积
可植入装置是硅酮涂层。 然而,
有机硅涂层对于许多应用是一个问题。 还
涂层必须手工涂敷,自动化该过程将不会
微不足道 一种气相沉积材料,其表现与
硅氧烷将是非常有利的。
聚对二甲苯将沉积在测试结构上,
预处理和涂层。 聚对二甲苯涂层的寿命试验
组件将由电压偏置盐水浸泡组成。 表面
电阻率变化将被用作各种
涂层技术 硅酮弹性体涂层试验器械性能
将用作聚对二甲苯涂层值的相对指标
技术.
英文摘要
Some of the most significant problems preventing the development of
implantable neural protheses for the neurologically handicapped involve
long-term insulation and protection of implanted devices. Specifically,
micromachined, thin-film recording and stimulating microelectrode probes
and miniature wires or cables connecting these electrodes with a source of
control and power must be protected from the hostile ionic environment of
extracellular fluids for decades if they are to be used reliably in humans.
The long-term goal of this research is to develop biocompatible coating
systems that will permit these neural prosthetic implants to function
reliably over the lifetime of an implant recipient.
The current most promising coatings for protection of the bond area of
implantable devices are the silicone coatings. However, the bulkiness of
the silicone coatings is a problem for many applications. Also, the
coatings must be applied by hand, and automating that procedure will not be
trivial. A vapor deposited material that performed as well as the
silicones would be highly advantageous.
Parylene will be deposited onto test structures following various surface
pre-treatments and coatings layers. Life tests of parylene coated
assemblies will consist of voltage biased saline soaks. Surface
resistivity changes will be used as an indicator of the efficacy of various
coatings techniques. Silicone elastomer coated test device performance
will be used as a relative indicator of the value of the parylene coating
techniques.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
ANTI BACTERIAL ADHERENCE TO OPHTHALMIC LENSES
-
批准号:2165147
-
项目类别:
-
资助金额:$10.0万
-
财政年份:1994
-
负责人:IH-HOUNG LOH
-
依托单位:
SURFACE MODIFICATION OF POLYMERS FOR ARTIFICIAL CORNEAS
-
批准号:2164652
-
项目类别:
-
资助金额:$7.88万
-
财政年份:1994
-
负责人:IH-HOUNG LOH
-
依托单位:
NOVEL POLYMER-COATED ION-EXCHANGE CHROMATOGRAPHY SUPPORT
-
批准号:3499034
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1993
-
负责人:IH-HOUNG LOH
-
依托单位:
BIODEGRADABLE VASCULAR GRAFTS
-
批准号:3502399
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1993
-
负责人:IH-HOUNG LOH
-
依托单位:
PEO STAR MOLECULES AS THROMBORESISTANT SURFACES
-
批准号:3502259
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1992
-
负责人:IH-HOUNG LOH
-
依托单位:
TOTALLY BIOABSORBABLE COMPOSITE BONE FIXATION DEVICE
-
批准号:3490676
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1992
-
负责人:IH-HOUNG LOH
-
依托单位:
BIOLOGICAL MATERIALS SEPARATION BY CONDUCTIVE MEMBRANES
-
批准号:3498516
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1990
-
负责人:IH-HOUNG LOH
-
依托单位:
NOVEL BIOELECTRODE FOR NEUROSCIENCE APPLICATIONS
-
批准号:3509261
-
项目类别:
-
资助金额:$26.11万
-
财政年份:1989
-
负责人:IH-HOUNG LOH
-
依托单位:
NOVEL BIOELECTRODE FOR NEUROSCIENCE APPLICATIONS
-
批准号:3504386
-
项目类别:
-
资助金额:$3.33万
-
财政年份:1989
-
负责人:IH-HOUNG LOH
-
依托单位:
NOVEL BIOELECTRODE FOR NEUROSCIENCE APPLICATIONS
-
批准号:3504385
-
项目类别:
-
资助金额:$1.67万
-
财政年份:1989
-
负责人:IH-HOUNG LOH
-
依托单位:
SURFACE MODIFICATION OF ABSORBABLE SUTURE MATERIALS
-
批准号:3490555
-
项目类别:
-
资助金额:$5.0万
-
财政年份:1989
-
负责人:IH-HOUNG LOH
-
依托单位:
海外基金