MANUFACTURING BIOELECTRONIC DEVICES VIA MULTIPHOTON FABRICATION
通过多光子制造制造生物电子设备
基本信息
- 批准号:EP/R003823/1
- 负责人:
- 金额:$ 12.84万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2017
- 资助国家:英国
- 起止时间:2017 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Electromagnetic fields affect a variety of tissues (e.g. bone, muscle, nerve and skin) and play important roles in biological processes (e.g. nerve sprouting, prenatal development and wound healing). This has inspired the development of electrically conducting devices for medical applications (e.g. cardiac pacemakers, neural electrodes/neuromodulation) that are manufactured from inorganic metals/alloys and are suited for long term application. Dr Hardy is an expert in the development of bioelectronic materials (particularly conducting polymers) for medical applications (drug delivery, neuromodulation and tissue regeneration) and seeks to use multiphoton fabrication (a high tech 3D printing technique) to print an emerging technology for healthcare applications (drug delivery devices that respond to electrical stimuli) feeding into both the materials- and healthcare-related industries which have multibillion pound turnovers and employ millions of people. Importantly, the project has the support of Manchester-based Kratos Analytical Ltd., is aligned with the oncoming Industry 4.0 revolution and supports the Northern Powerhouse.
电磁场影响多种组织(如骨骼、肌肉、神经和皮肤),并在生物过程(如神经发芽、产前发育和伤口愈合)中发挥重要作用。这激发了医疗应用(例如心脏起搏器,神经电极/神经调节)的导电设备的发展,这些设备由无机金属/合金制造,适合长期应用。哈迪博士是生物电子材料(特别是导电聚合物)开发方面的专家,用于医疗应用(药物输送,神经调节和组织再生),并寻求使用多光子制造(一种高科技3D打印技术)来打印一种用于医疗保健应用的新兴技术(对电刺激做出反应的药物输送设备),这些技术将用于材料和医疗保健相关行业,这些行业拥有数十亿英镑的营业额,雇佣了数百万人。重要的是,该项目得到了总部位于曼彻斯特的Kratos分析有限公司的支持,与即将到来的工业4.0革命保持一致,并支持北方振兴计划。
项目成果
期刊论文数量(9)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Wirelessly triggered bioactive molecule delivery from degradable electroactive polymer films
- DOI:10.1002/pi.6089
- 发表时间:2020-08-06
- 期刊:
- 影响因子:3.2
- 作者:Ashton, Mark D.;Appen, Isabel C.;Hardy, John G.
- 通讯作者:Hardy, John G.
Controlled Bioactive Delivery Using Degradable Electroactive Polymers.
- DOI:10.1021/acs.biomac.2c00516
- 发表时间:2022-07-11
- 期刊:
- 影响因子:6.2
- 作者:Ashton, Mark D.;Cooper, Patricia A.;Municoy, Sofia;Desimone, Martin F.;Cheneler, David;Shnyder, Steven D.;Hardy, John G.
- 通讯作者:Hardy, John G.
Creating 3D Objects with Integrated Electronics via Multiphoton Fabrication In Vitro and In Vivo
- DOI:10.1002/admt.202201274
- 发表时间:2023-03-12
- 期刊:
- 影响因子:6.8
- 作者:Baldock, Sara J.;Kevin, Punarja;Hardy, John G.
- 通讯作者:Hardy, John G.
Biocompatibility investigation of hybrid organometallic polymers for sub-micron 3D printing via laser two-photon polymerisation
通过激光双光子聚合进行亚微米 3D 打印的混合有机金属聚合物的生物相容性研究
- DOI:10.3390/ma122333932
- 发表时间:2019
- 期刊:
- 影响因子:3.4
- 作者:Balciunas E.
- 通讯作者:Balciunas E.
3D printing hybrid organometallic polymer-based biomaterials via laser two-photon polymerization
- DOI:10.1002/pi.5909
- 发表时间:2019-09-10
- 期刊:
- 影响因子:3.2
- 作者:Balciunas, Evaldas;Baldock, Sara J.;Baltriukiene, Daiva
- 通讯作者:Baltriukiene, Daiva
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
John Hardy其他文献
Variant Alzheimer’s disease with spastic paraparesis
伴有痉挛性截瘫的变异型阿尔茨海默病
- DOI:
- 发表时间:
2000 - 期刊:
- 影响因子:9.9
- 作者:
A. Verkkoniemi;M. Somer;J. Rinne;L. Myllykangas;R. Crook;John Hardy;M. Viitanen;H. Kalimo;M. Haltia - 通讯作者:
M. Haltia
Journal Pre-proof Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells
期刊预证明通过 TLR4 激活废除 LRRK2 依赖性 Rab10 磷酸化以及免疫细胞中诱发细胞因子释放的改变
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
Iqra Nazish;C. Arber;T. Piers;Tom T. Warner;John Hardy;Patrick A. Lewis;Jennifer M. Pocock;Rina Bandopadhyay - 通讯作者:
Rina Bandopadhyay
Genome-wide association analysis of Dementia with Lewy bodies reveals unique genetic architecture
痴呆与路易体的全基因组关联分析揭示了独特的遗传结构
- DOI:
- 发表时间:
2017 - 期刊:
- 影响因子:0
- 作者:
Rita Guerreiro;Owen A. Ross;Célia Kun;Dena G. Hernandez;Tatiana Orme;John D. Eicher;Claire Shepherd;L. Parkkinen;Lee Darwent;Michael G. Heckman;Sonja;W. Scholz;Juan C. Troncoso;O. Pletnikova;Olaf Ansorge;J. Clarimón;Alberto;Lleó;E. Morenas;Lorraine Clark;Lawrence Honig;Karen Marder;A. Lemstra;E. Rogaeva;P. S. George;E. Londos;Henrik;Zetterberg;I. Barber;A. Braae;K. Brown;Kevin Morgan;Claire;Troakes;S. Al;T. Lashley;J. Holton;Y. Compta;Vivianna;Van Deerlin;G. Serrano;Thomas G. Beach;S. Lesage;D. Galasko;E. Masliah;Isabel Santana;P. Pástor;M. Diez;M. Aguilar;Pentti;J. Tienari;L. Myllykangas;M. Oinas;T. Revesz;Andrew J. Lees;F. Brad;Boevé;R. C. Petersen;T. Ferman;V. Escott;;Radford;Nigel J. Cairns;John C. Morris;S. Pickering;David Mann;M. Glenda;Halliday;John Hardy;J. Trojanowski;Dennis W. Dickson;Andy Singleton;David Stone;J. Bras - 通讯作者:
J. Bras
Genetic predisposition to increased blood cholesterol and Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: A Mendelian triglyceride lipid levels and risk of Alzheimer disease: A Mendelian randomization analysis randomization analysis
血液胆固醇升高的遗传倾向和血液胆固醇和甘油三酯脂质水平升高的遗传倾向以及阿尔茨海默病的风险:孟德尔甘油三酯脂质水平和阿尔茨海默病的风险:孟德尔随机化分析
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
P. Proitsi;Michelle K. Lupton;L. Velayudhan;Steven J. Newhouse;I. Fogh;Magda Tsolaki;M. Daniilidou;M. Pritchard;I. Kloszewska;H. Soininen;Patrizia Mecocci;Robert Stewart;Pak C. Sham;S. Lovestone;John Powell;Denise Harold;R. Sims;A. Gerrish;J. Chapman;V. Escott;R. Abraham;P. Hollingworth;M. Hamshere;Jaspreet Singh;Kimberley Dowzell;Amy J. Williams;N. Jones;C. Thomas;A. Stretton;Angharad R. Morgan;Kate Williams;Carol Brayne;D. Rubinsztein;Michael Gill;Brian A. Lawlor;A. Lynch;Kevin Morgan;K. Brown;P. Passmore;David Craig;B. McGuinness;Janet A. Johnston;S. Todd;Clive Holmes;David M. Mann;A. D. Smith;Seth Love;Patrick G. Kehoe;John Hardy;Rita Guer;Andrew B. Singleton;S. Mead;Nick Fox;M. Rossor;J. Collinge;Wolfgang Maier;Frank Jessen;R. Heun;Britta Schu¨rmann;Alfredo Ramirez;Tim Becker;C. Herold;A. Lacour;D. Drichel;H. Bussche;Isabella Heuser;J. Kornhuber;J. Wiltfang;M. Dichgans;Lutz Fro¨lich;H. Hampel;Michael Hu¨ll;Dan Rujescu;Alison M Goate;J. Kauwe;C. Cruchaga;P. Nowotny;John C. Morris;K. Mayo;G. Livingston;N. Bass;H. Gurling;A. McQuillin;R. Gwilliam;P. Deloukas;Markus M. No¨then;P. Holmans;M. O'Donovan;Michael J.Owen;Julie Williams - 通讯作者:
Julie Williams
The genetics of neurodegenerative diseases is the genetics of age-related damage clearance failure
神经退行性疾病的遗传学就是与年龄相关的损伤清除失败的遗传学。
- DOI:
10.1038/s41380-025-02911-7 - 发表时间:
2025-01-29 - 期刊:
- 影响因子:10.100
- 作者:
John Hardy;Valentina Escott-Price - 通讯作者:
Valentina Escott-Price
John Hardy的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('John Hardy', 18)}}的其他基金
Understanding the genes for Parkinson's disease
了解帕金森病的基因
- 批准号:
MR/N026004/1 - 财政年份:2016
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
Risk and Modifying factors in Fronto Temporal Dementia
额颞叶痴呆的风险和改变因素
- 批准号:
MR/L501542/1 - 财政年份:2014
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
Using genetic variability in whole transcriptome expression in cells and tissues to understand the pathogenesis of Parkinson's and Alzheimer's disease
利用细胞和组织中全转录组表达的遗传变异来了解帕金森病和阿尔茨海默病的发病机制
- 批准号:
MR/K01417X/1 - 财政年份:2013
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
Mapping the genetic architecture of global gene and exon expression in the human brain to understand common diseases
绘制人脑全局基因和外显子表达的遗传结构,以了解常见疾病
- 批准号:
G0901254/1 - 财政年份:2010
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
Behavioral Ecology of Central American Birds
中美洲鸟类的行为生态学
- 批准号:
7609735 - 财政年份:1976
- 资助金额:
$ 12.84万 - 项目类别:
Standard Grant
相似海外基金
Can we heal people using electricity? Developing fundamental understanding and bioelectronic devices to exploit bioelectricity in bioengineering.
我们可以用电来治愈人们吗?
- 批准号:
MR/X032159/1 - 财政年份:2024
- 资助金额:
$ 12.84万 - 项目类别:
Fellowship
Bioelectronic materials and devices for smart drug delivery (BioEMat)
用于智能药物输送的生物电子材料和设备(BioEMat)
- 批准号:
EP/Y008529/1 - 财政年份:2023
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant
ASCENT: BioNet: A distributed network of bioelectronic devices for closed-loop control of physiological processes
ASCENT:BioNet:用于生理过程闭环控制的生物电子设备分布式网络
- 批准号:
2023849 - 财政年份:2020
- 资助金额:
$ 12.84万 - 项目类别:
Standard Grant
Material Synthesis for applications in Bioelectronic Devices
生物电子器件应用的材料合成
- 批准号:
2275815 - 财政年份:2019
- 资助金额:
$ 12.84万 - 项目类别:
Studentship
Conducting polymer thin films for high-performance organic bioelectronic devices
用于高性能有机生物电子器件的导电聚合物薄膜
- 批准号:
469025-2014 - 财政年份:2017
- 资助金额:
$ 12.84万 - 项目类别:
Vanier Canada Graduate Scholarship Tri-Council - Doctoral 3 years
Conducting polymer thin films for high-performance organic bioelectronic devices
用于高性能有机生物电子器件的导电聚合物薄膜
- 批准号:
469025-2014 - 财政年份:2016
- 资助金额:
$ 12.84万 - 项目类别:
Vanier Canada Graduate Scholarship Tri-Council - Doctoral 3 years
Conducting polymer thin films for high-performance organic bioelectronic devices
用于高性能有机生物电子器件的导电聚合物薄膜
- 批准号:
469025-2014 - 财政年份:2015
- 资助金额:
$ 12.84万 - 项目类别:
Vanier Canada Graduate Scholarship Tri-Council - Doctoral 3 years
Conducting polymer thin films for bioelectronic devices
用于生物电子器件的导电聚合物薄膜
- 批准号:
465700-2014 - 财政年份:2014
- 资助金额:
$ 12.84万 - 项目类别:
University Undergraduate Student Research Awards
Conducting polymer thin films for high-performance organic bioelectronic devices
用于高性能有机生物电子器件的导电聚合物薄膜
- 批准号:
469025-2014 - 财政年份:2014
- 资助金额:
$ 12.84万 - 项目类别:
Vanier Canada Graduate Scholarship Tri-Council - Doctoral 3 years
Diamond devices for bioelectronic applications - invited resubmission
用于生物电子应用的金刚石器件 - 邀请重新提交
- 批准号:
EP/F026110/1 - 财政年份:2008
- 资助金额:
$ 12.84万 - 项目类别:
Research Grant














{{item.name}}会员




