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PSYCHOBIOLOGY OF ALCOHOLISM IN WOMEN

PSYCHOBIOLOGY OF ALCOHOLISM IN WOMEN
女性酗酒的心理生物学
批准号:
3801972
负责人:
D GEORGE
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
研究表明酒精中毒的病理生理学可能有很大的不同 男人和女人之间。 为了探索这种可能性,我们采用了 几种药理学挑战范式来比较行为和 男性和女性酗酒者之间的内分泌反应。 初步 我们的结果的分析表明,m-CPP产生最小的 行为效应 这对应于从类型I获得的响应 男性酗酒者(晚发)在一项单独的研究中证明。 在 相比之下,没有一个妇女经历了m-CPP诱导的“饮酒欲望”, 在约40%的II型(晚期)患者中证实发生缓解。 男性酗酒者。
英文摘要
Studies suggest the pathophysiology of alcoholism may differ significantly between men and women. To explore this possibility we have employed several pharmacological challenge paradigms to compare the behavioral and endocrine responses between male and female alcoholics. Preliminary analysis of our results show that the m-CPP gives rise to minimal behavioral effects. This corresponds to the response obtained from Type I male alcoholics (late onset) demonstrated in a separate study. In contrast, none of the women experienced a m-CPP induced "desire to drink" response demonstrated to occur in approximately 40% of the Type II (late onset) male alcoholics.
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会议论文
PSYCHOLOGICAL AND BIOLOGICAL CHARACTERIZATION OF SMOKING WITHDRAWAL IN ALCOHOLICS
PSYCHOBIOLOGY OF ALCOHOLISM IN WOMEN
FAMILY STUDIES OF ALCOHOLISM
INTRAVENOUS PROCAINE IN ALCOHOLICS AND ADULT CHILDREN OF ALCOHOLICS
国内基金
海外基金
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  • 项目类别:
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  • 项目类别:
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