Control of Salvador-Warts-Hippo Pathway activity in Drosophila and mammals
Control of Salvador-Warts-Hippo Pathway activity in Drosophila and mammals
批准号:
nhmrc : 566700
负责人:
Prof Kieran Harvey
金额:
$34.28万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
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英文摘要
The primary function of the Salvador-Warts-Hippo (SWH) pathway is to dictate the appropriate size of organs in developing animals. Deregulation of this pathway results in vastly overgrown organs and can lead to the formation of cancer in humans. Our study will provide important insights into how the size of organs are controlled during development by identifying new SWH pathway components. We will also increase understanding of diseases that arise due to aberrant tissue growth, such as cancer.
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Defining how signalling pathways cooperate to regulate organ size
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批准号:DP230101406
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项目类别:Discovery Projects
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资助金额:$27.24万
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财政年份:2023
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负责人:Prof Kieran Harvey
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依托单位:
Investigating Hippo-regulated transcription at single molecule resolution
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批准号:DP220102523
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项目类别:Discovery Projects
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资助金额:$36.25万
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财政年份:2022
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负责人:Prof Kieran Harvey
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依托单位:
How neurons maintain their fate
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批准号:DP190101743
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项目类别:Discovery Projects
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资助金额:$31.94万
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财政年份:2019
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负责人:Prof Kieran Harvey
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依托单位:
The Hippo pathway and melanoma growth
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批准号:nhmrc : 1145166
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项目类别:Project Grants
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资助金额:$54.73万
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财政年份:2018
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负责人:Prof Kieran Harvey
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依托单位:
The Hippo pathway and melanoma growth
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批准号:nhmrc : GNT1145166
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项目类别:Project Grants
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资助金额:$80.95万
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财政年份:2018
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负责人:Prof Kieran Harvey
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依托单位:
The Hippo signalling pathway in dividing and non-dividing cells
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批准号:DP180102044
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项目类别:Discovery Projects
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资助金额:$31.23万
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财政年份:2018
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负责人:Prof Kieran Harvey
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依托单位:
Control of organ size and cancer by the Hippo pathway
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批准号:nhmrc : GNT1078220
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项目类别:Research Fellowships
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资助金额:$61.16万
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财政年份:2015
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负责人:Prof Kieran Harvey
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依托单位:
Control of transcription by the Hippo pathway
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批准号:nhmrc : GNT1080131
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项目类别:Project Grants
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资助金额:$40.9万
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财政年份:2015
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负责人:Prof Kieran Harvey
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依托单位:
Control of transcription by the Hippo pathway
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批准号:nhmrc : 1080131
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项目类别:Project Grants
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资助金额:$42.19万
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财政年份:2015
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负责人:Prof Kieran Harvey
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依托单位:
Control of organ size and cancer by the Hippo pathway
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批准号:nhmrc : 1078220
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项目类别:Research Fellowships
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资助金额:$42.58万
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财政年份:2015
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负责人:Prof Kieran Harvey
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依托单位:
Characterisation of two new kinases in the Hippo tumour suppressor pathway
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批准号:nhmrc : 1060090
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项目类别:Project Grants
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资助金额:$36.71万
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财政年份:2014
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负责人:Prof Kieran Harvey
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依托单位:
Wbp2, a new regulator of the Hippo tumor suppressor pathway
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批准号:nhmrc : 1020318
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项目类别:Project Grants
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资助金额:$39.07万
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财政年份:2012
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负责人:Prof Kieran Harvey
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依托单位:
GTPase regulation of the Hippo organ size-control pathway
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批准号:nhmrc : 1020316
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项目类别:Project Grants
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资助金额:$38.03万
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财政年份:2012
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负责人:Prof Kieran Harvey
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依托单位:
Tao kinase, a new member of the Hippo tumour suppressor pathway
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批准号:nhmrc : 1032551
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项目类别:Project Grants
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资助金额:$40.35万
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财政年份:2012
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负责人:Prof Kieran Harvey
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依托单位:
How does Fat cadherin control organ size in Drosophila, and cancer in humans?
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批准号:DP0985049
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项目类别:Discovery Projects
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资助金额:$20.08万
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财政年份:2009
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负责人:Prof Kieran Harvey
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依托单位:
Control of organ size during development and disease by the Salvadore-Warts-Hippo pathway
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批准号:nhmrc : 509347
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项目类别:Career Development Fellowships
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资助金额:$22.12万
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财政年份:2008
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负责人:Prof Kieran Harvey
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依托单位:
Examination of the mechanism by which the salvador/warts/hippo complex restricts cell growth and number
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批准号:nhmrc : 400335
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项目类别:NHMRC Project Grants
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资助金额:$18.92万
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财政年份:2006
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负责人:Prof Kieran Harvey
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依托单位:
国内基金
海外基金
支架蛋白Salvador1调控Hippo-YAP/TAZ信号通路抑制软骨内成骨的作用及机制
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批准号:81902177
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项目类别:青年科学基金项目
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资助金额:21.0万元
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批准年份:2019
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负责人:杨玮
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依托单位: