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CARBOHYDRATE RECEPTORS FOR HUMAN PATHOGENS

CARBOHYDRATE RECEPTORS FOR HUMAN PATHOGENS
人类病原体的碳水化合物受体
批准号:
3752081
负责人:
D D ROBERTS
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

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中文摘要
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英文摘要
Adhesive specificities of Staphylococcus aureus, some Enterococcus species, Candida albicans, and elementary bodies of Chlamydia trachomatis are being examined. These have been screened for binding to extracellular matrix proteins and glycoproteins and glycolipids of known structure and to glycoconjugates isolated from target tissues to which the pathogens adhere. Where possible, inhibitors of each binding specificity will be identified using the solid phase assays and then tested using in vitro cytoadherence as says and in vivo infection assays to determine the role of each in cytoadherence and initiation of infection.
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GLYCOCONJUGATE ANTIGENS EXPRESSED IN CANCER CELLS
CELL INTERACTIONS WITH THROMBOSPONDIN
CARBOHYDRATE RECEPTORS FOR HUMAN PATHOGENS
GLYCOLIPID ANTIGENS EXPRESSED IN CANCER CELLS