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CARBOHYDRATE RECEPTORS FOR HUMAN PATHOGENS

CARBOHYDRATE RECEPTORS FOR HUMAN PATHOGENS
人类病原体的碳水化合物受体
批准号：
3813428
负责人：
D D ROBERTS
金额：
$0.0万
依托单位：
DIVISION OF CANCER BIOLOGY AND DIAGNOSIS
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3813428
关键词：
Candida albicans Chlamydia trachomatis Mycoplasma pneumoniae adhesin antireceptor antibody bacterial antigens binding proteins carbohydrate receptor carbohydrate sequence carbohydrate structure cell adhesion chlamydial disease fibronectins glycolipids glycoproteins heparin human tissue laminin monoclonal antibody mycoplasmal pneumonia receptor binding sialate sulfates tissue /cell culture

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中文摘要
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英文摘要
Adhesive specificities of some Enterococcus species, Candida albicans, and elementary bodies of Chlamydia trachomatis are being examined. These will be screened for binding to glycoproteins and glycolipids of known structure and to glycoconjugates isolated from target tissues to which the pathogens adhere. Where possible, inhibitors of each binding specificity will be identified using the solid phase assays and then tested using in vitro cytoadherence assays and in vivo infection assays to determine the role of each in cytoadherence and initiation of infection.
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会议论文
GLYCOCONJUGATE ANTIGENS EXPRESSED IN CANCER CELLS
CARBOHYDRATE RECEPTORS FOR HUMAN PATHOGENS
CELL INTERACTIONS WITH THROMBOSPONDIN
GLYCOLIPID ANTIGENS EXPRESSED IN CANCER CELLS
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