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CHARACTERIZATION OF A NOVEL HTLV-II CELL LINE

CHARACTERIZATION OF A NOVEL HTLV-II CELL LINE
新型 HTLV-II 细胞系的表征
批准号：
3748273
负责人：
M RUTA
金额：
$0.0万
依托单位：
BUREAU OF HEALTH PLANNING AND RESOURCES DEVELOPMENT
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3748273
关键词：
Retroviridae disease aplastic anemia blood cells cell bank /registry cytokine receptors genetic strain human T cell lymphotropic virus type 2 human tissue interleukin 2 northern blottings virus classification western blottings

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中文摘要
翻译
我们以前从一个再生障碍性患者身上分离出一个细胞系（JR）
英文摘要
We previously isolated a cell line (JR) from a patient with aplastic anemia that produces HTLVII. We have characterized this cell line and the virus it produces. In addition, a second cell line derived from cord blood cells infected with the JR virus. This cell line remains IL-2 dependent and grows slowly. Western blot analysis of the two cell lines shows protein profiles similar to to other HTLV-II viral strains. Northern blot analysis of the cell lines used the IL-2 receptor, showed low levels of IL-2 receptor RNA compared to other infected cell lines. We are investigating the use of the JR-cord blood cell line as a model for early HTLV infection. Our studies on the isolation of JR cell line is being prepared for publication.
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CHARACTERIZATION OF A NOVEL HTLV-II CELL LINE
HTLV-II ELISA AND WESTERN BLOTS
FGF RECEPTOR EXPRESSION IN TUMORS
SEROLOGIC MARKERS OF HTLV-I/II INFECTION
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