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IN VITRO FOLDING AND ASSEMBLY OF MHC MOLECULES

IN VITRO FOLDING AND ASSEMBLY OF MHC MOLECULES
MHC 分子的体外折叠和组装
批准号：
3790856
负责人：
D H MARGULIES
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3790856
关键词：
MHC class I antigen protein folding

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中文摘要
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英文摘要
The focus of this laboratory has been the MHC class I molecule, classically considered a molecular heterodimer consisting of a 46 kd polymorphic heavy chain, exemplified by the murine H-2K, D, and L molecules (analogous to the human HLA-A, -B, and -C molecules), that is non-covalently assembled with the 12 kd monomorphic light chain, beta2-microglobulin. Our objectives in this project have been to develop an in vitro system for examining early events in the folding and assembly of the MHC molecules.
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会议论文
MOLECULAR GENETIC ANALYSIS OF LYMPHOCYTE FUNCTION
IN VITRO MEASUREMENT OF BINDING OF SELF AND ANTIGENIC PEPTIDES TO MHC MOLECULES
MOLECULAR GENETIC ANALYSIS OF LYMPHOCYTE FUNCTION
MOLECULAR GENETIC ANALYSIS OF LYMPHOCYTE FUNCTION
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