FINLAND STUDIES OF NUTRITION AND CANCER

芬兰的营养与癌症研究

• 批准号: 3874578
• 负责人: D ALBANES
• 金额: --
• 依托单位: DIVISION OF CANCER PREVENTION AND CONTROL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3874578
• 关键词: Scandinavian country; breast neoplasms; cancer prevention; cancer risk; carcinogenesis inhibitor; colon neoplasms; dietary constituent; dietary lipid; dietary trace element; genetic markers; human subject; lung neoplasms; neoplasm /cancer nutrition therapy; neoplastic growth; nutrition aspect of cancer; nutrition related neoplasm /cancer; nutrition related tag; retinoids; selenium; tocopherols; vitamin therapy

The important relationship of diet and nutrition in the development of cancer has become well known through various research efforts. Laboratory studies have shown cancer inhibitory function for various natural and synthetic nutrients in various models, which have been corroborated by human epidemiologic studies of nutrient intake, tissue levels, and cancer incidence. The objectives of these etiologic studies are to (1) assess the role of fats, selenium, and vitamins A, E, and C in breast cancer development; and (2) evaluate the relation of intake of various nutrients to subsequent cancer, particularly breast, colon, and lung. The project includes two studies. The first is a breast cancer case-control study of fats, total calories, selenium, and vitamins A, E, and C. The role of various anthropometric measurements, genetic markers for breast cancer, and reproductive factors are being explored. The second project is a comparison of nutrient intakes in cases and reference subjects identified from an existing large cohort with prediagnostic baseline dietary histories. Associations between various dietary components and several cancers will be assessed.

饮食与营养在猪生长发育中的重要关系 通过各种研究工作，癌症已变得众所周知。实验室 研究表明，各种天然和 各种模型中的合成营养素，这已经得到证实， 营养摄入、组织水平和癌症的人类流行病学研究 发病率。这些病因学研究的目的是（1）评估 脂肪、硒和维生素A、E和C在乳腺癌中的作用 评价各种营养素摄入量的关系 尤其是乳腺癌结肠癌和肺癌项目 包括两项研究。第一个是乳腺癌病例对照研究， 脂肪、总热量、硒和维生素A、E和C。的作用 各种人体测量，乳腺癌的遗传标记， 生殖因素正在探索中。第二个项目是比较 营养素摄入量的情况下，并从一个确定的参考对象， 现有具有诊断前基线饮食史的大型队列。 各种饮食成分和几种癌症之间的联系将被 评估。