FELS EARLY NUTRITION AND GROWTH STUDY

FLS 早期营养和生长研究

• 批准号: 5201394
• 负责人: D ALBANES
• 金额: --
• 依托单位: DIVISION OF CANCER PREVENTION AND CONTROL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5201394
• 关键词: adolescence (12-20); body composition; body height; body physical characteristic; body weight; breast neoplasms; caloric dietary content; cancer risk; child (0-11); child physical development; developmental nutrition; diet; dietary constituent; dietary fiber; dietary lipid; dietary proteins; female; human puberty; human subject; nutrition aspect of cancer; nutrition related neoplasm /cancer; nutrition related tag; obesity; reproductive development; vitamins

This project is designed to investigate the relation of childhood nutrition to breast cancer risk factors, including age at menarche, adult height, weight, and fatness. Secondary purposes include tracking the development of overweight and obesity from birth through young adulthood, identification of possible "sensitive" or high-risk periods (wit respect to obesity) in childhood and, more important, to identify the contribution of diet to the development of childhood and adult obesity. Detailed anthropometric data (height, weight, skinfold thickness, etc.) and demographic characteristics available from a computer data base from the Fels Study and the Division of Human Biology of the Wright State School of Medicine included up to 18 annual dietary and anthropometric assessments for 106 girls. Calorie, macro- and micronutrient data were linked to the existing anthropometry computer file, including later adult height and weight. Nutrient composition has been calculated using the latest version of the USDA Handbook series. Nutrients include the following: total energy (kilocalories); total fat, protein, and carbohydrat saturated, polyunsaturated, and monounsaturated fat; cholesterol; dietary fiber; and vitamins and minerals (from food and supplementary sources). This study is being conducted collaboratively with scientists at the Wright State School of Medicine in Yellow Springs, Ohio. Data analysis is currently underway.

该项目旨在调查儿童营养的关系 乳腺癌危险因素，包括初潮年龄、成年身高、 体重和肥胖程度。 次要目的包括跟踪 从出生到青少年时期超重和肥胖的发展 成年期，识别可能的“敏感”或高风险时期（机智） 儿童时期的肥胖问题，更重要的是，确定 饮食对儿童和成人肥胖发展的贡献。 详细的人体测量数据（身高、体重、皮褶厚度等）和 人口统计特征可从计算机数据库中获得 菲尔斯研究和莱特州人类生物学部门 医学院包括多达 18 项年度饮食和人体测量 对 106 名女孩的评估。 卡路里、常量和微量营养素数据 链接到现有的人体测量计算机文件，包括后来的成人 身高和体重。 营养成分的计算采用 美国农业部手册系列的最新版本。 营养素包括 以下：总能量（千卡）；总脂肪、蛋白质和碳水化合物 饱和脂肪、多不饱和脂肪和单不饱和脂肪；胆固醇;饮食 纤维;维生素和矿物质（来自食物和补充品）。 这项研究是与科学家合作进行的 俄亥俄州黄泉市赖特州立医学院。 数据分析 目前正在进行中。