LESIONS OF SELENIUM-VITAMIN E DEFICIENCY IN DIFFERENT STRAINS OF MICE

不同品系小鼠硒维生素E缺乏症的病变

• 批准号: 3858173
• 负责人: V J FERRANS
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3858173
• 关键词: dietary supplements; disease /disorder model; genetic strain; laboratory mouse; myocardium disorder; nutrition related tag; selenium; silver; vitamin E deficiency

A mouse model of selenium-vitamin E deficiency was developed in which the deficiency disease was potentiated by the addition of silver acetate to the basal diet. Of 3 strains of mice tested for relative susceptibility the C57BL strain was found to be most satisfactory in terms of producing myocardial lesions.

建立了一种硒-维生素E缺乏的小鼠模型， 通过添加银醋酸盐， 基础饮食 对3个品系的小鼠进行了相对敏感性试验 发现C57 BL菌株在生产方面最令人满意 心肌病变