CHROMOSOME CHANGE IN PROSTATE, KIDNEY AND TESTIS CANCER

前列腺癌、肾癌和睾丸癌的染色体变化

• 批准号: 3938925
• 负责人: AVERY A SANDBERG
• 金额: --
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3938925
• 关键词: cholera toxin; chromosome disorders; cytogenetics; developmental genetics; human subject; kidney neoplasms; metastasis; neoplasm /cancer genetics; prostate neoplasms; testis neoplasms; tissue /cell culture

Although a paucity of information exists regarding cytogenetic alterations in most human solid tumors, particularly little is known about cancers of the prostate, kidney, and testes. This project will focus upon identifying both primary and secondary chromosome changes in an attempt to correlate recognized chromosome alterations with clinical features important to these cancers. With the significant clinical resources available to this project, our documented expertise in tumor cytogenetics, and our recent advances in cell culture techniques, we should be able to provide important new information regarding the karyotypic profile of these important cancers.

尽管关于细胞遗传学的信息很少 大多数人类实体肿瘤的改变，特别是很少 已知前列腺癌、肾癌和睾丸癌。这 该项目将专注于确定主要和次要 染色体的变化试图将已识别的 具有重要临床特征的染色体改变 癌症。有了大量的临床资源， 项目，我们在肿瘤细胞遗传学方面的专业知识，以及我们的 细胞培养技术的最新进展，我们应该能够 提供有关核型的重要新信息 这些重要癌症的概况。