RENAL BIOPSY PATHOLOGY IN SYSTEMIC LUPUS ERYTHEMATOSUS

不同形式的骨质疏松症的发病机制 狼疮性肾炎正在调查中。肾脏的详细分析 正在对患者的样本进行活组织病理学检查 系统性红斑狼疮。活组织检查按以下方式分类 狼疮性肾炎的主要类别，以及对 半定量标尺用于特定的组织学改变 活动度和慢性硬化性特征。这个 免疫复合体沉积和淋巴样细胞的类型 与肾单位不同节段的相互作用 通过免疫组织学技术和电子技术进行研究 显微镜。这些方法促进了对 不同类型免疫抑制剂用于止血的效果观察 狼疮性肾炎的进展，他们将加强我们的 了解这种疾病的发病机制。

The pathogenetic mechanisms underlying the different forms of lupus nephritis are being investigated. Detailed analysis of renal biopsy pathology is being conducted on specimens from patients with systemic lupus erythematosus. Biopsies are classified by major category of lupus nephritis, as well as scored on a semiquantitative scale for specific histologic changes indicating the degree of activity and of chronic sclerosing features. The patterns of immune complex deposition and lymphoid cell interaction with different segments of the nephron are being investigated by immunohistologic techniques and electron microscopy. These approaches have facilitated the analysis of the effects of various types of immunosuppressive agents used to halt the progression of lupus nephritis and they will enhance our understanding of the pathogenesis of this disease.