STUDY OF OCULAR GLIAL CELLS INVOLVEMENT IN UVEITIS

这项工作涉及葡萄膜视网膜炎症性疾病的机制。这项研究 重点评估驻留细胞在靶器官中的作用 水平。米勒细胞与T淋巴细胞株相互作用的研究 在试管中。米勒细胞对T淋巴细胞的两种相反作用 发现在不同的培养条件下可以表达的增殖 条件。对抗原诱导的聚合反应的抑制作用 辅助性T淋巴细胞可以用各种药物来调节，这些药物允许 米勒细胞作为抗原提呈细胞发挥作用。

The work concerns uveoretinal inflammatory disease mechanisms. The study focused on evaluating the role of resident cells at the target organ level. Muller cells interactions with T-lymphocyte cell line was studied in vitro. Two opposite effects of Muller cells on T-lymphocytes proliferation were found that could be expressed under different culture conditions. An inhibitory effect on antigen driven poliferation of T-helper lymphocytes could be modulated with various drugs that allowed the Muller cells to function as antigen presenting cells.