CiC 2017: Crick Idea to Innovation (i2i)

CiC 2017：从批判创意到创新 (i2i)

• 批准号: MC_PC_17179
• 负责人: Veronique Birault
• 金额: $ 75.18万
• 依托单位: The Francis Crick Institute
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_17179
• 关键词: CiC; 2017; Crick; Idea; Innovation

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets

开发无细胞分裂荧光素酶生化测定作为筛选具有挑战性的蛋白质-蛋白质相互作用靶点抑制剂的工具

• DOI: 10.12688/wellcomeopenres.15675.2
• 发表时间: 2020
• 期刊: Wellcome Open Research
• 作者: Cooley R

Dynamic contrast-enhanced magnetic resonance imaging quantification of leukemia-induced changes in bone marrow vascular function.

• DOI: 10.3324/haematol.2020.277269
• 发表时间: 2021-08-01
• 期刊: Haematologica
• 影响因子: 10.1
• 作者: Gomes AL;Gribben J;Siow B;Passaro D;Bonnet D
• 通讯作者: Bonnet D

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.

• DOI: 10.1016/j.cell.2021.01.002
• 发表时间: 2021-02-04
• 期刊: Cell
• 影响因子: 64.5
• 作者: Litchfield K;Reading JL;Puttick C;Thakkar K;Abbosh C;Bentham R;Watkins TBK;Rosenthal R;Biswas D;Rowan A;Lim E;Al Bakir M;Turati V;Guerra-Assunção JA;Conde L;Furness AJS;Saini SK;Hadrup SR;Herrero J;Lee SH;Van Loo P;Enver T;Larkin J;Hellmann MD;Turajlic S;Quezada SA;McGranahan N;Swanton C
• 通讯作者: Swanton C

Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2-specific T-cells.

• DOI: 10.1183/13993003.00285-2021
• 发表时间: 2022-01
• 期刊: The European respiratory journal
• 作者: Riou C;Schäfer G;du Bruyn E;Goliath RT;Stek C;Mou H;Hung D;Wilkinson KA;Wilkinson RJ
• 通讯作者: Wilkinson RJ

Ultra-fast proteomics with Scanning SWATH.

• DOI: 10.1038/s41587-021-00860-4
• 发表时间: 2021-07
• 期刊: Nature biotechnology
• 影响因子: 46.9
• 作者: Messner CB;Demichev V;Bloomfield N;Yu JSL;White M;Kreidl M;Egger AS;Freiwald A;Ivosev G;Wasim F;Zelezniak A;Jürgens L;Suttorp N;Sander LE;Kurth F;Lilley KS;Mülleder M;Tate S;Ralser M
• 通讯作者: Ralser M