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RESPONSE OF MEASURES OF IRON STATUS TO INDIVIDUALIZED DOSES OF IV IRON DEXTRAN

RESPONSE OF MEASURES OF IRON STATUS TO INDIVIDUALIZED DOSES OF IV IRON DEXTRAN
铁状态测量对个体化剂量右旋糖酐铁静脉注射的反应
批准号：
5218415
负责人：
GARY R MATZKE
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5218415
关键词：
clinical research dextrans dosage drug interactions erythropoietin ferritin human subject intravenous administration iron compounds iron metabolism pharmacokinetics

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中文摘要
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英文摘要
The purpose of this study is to determine the relationship between several indices of systemic stores of iron with the surrogate gold standard, serum ferritin, for measurement of iron status, and erythropoietin sensitivity. This study will also assess the sensitivity and specificity of the response of these various measures of iron stores to an intravenous dose of iron dextran. Finally, the relationship between administered iron dose, the multiple iron indices, and erythropoietin sensitivity will be evaluated.
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