MR GUIDED THERMAL ABLATION OF ABDOMINAL TUMORS

本试验的目的是：描述磁共振(MR)引导的软组织转移瘤热消融的安全性，并描述使用射频发生器作为热源通过热消融在肿瘤内产生的肿瘤坏死率。患者只有那些用标准措施干预失败的实体肿瘤患者，或者那些被认为系统治疗无效的患者。患者不能作为手术切除的对象。已有8名患者接受治疗(11名登记)。三名患者参加了不同病变的消融治疗。到目前为止，1名受试者完全应答，5名登记的患者病情稳定，3名患者病情进展，1名患者被取消，最后1名患者尚未进行分析。这项试验继续吸引患者。

The objectives of this trial are: to describe the safety of Magnetic Resonance (MR) guided thermal ablation of soft tissue metastases and to describe the fraction of tumor necrosis that can be generated within tumors through thermal ablation using a radiofrequency (RF) generator as the heat source. Patients are only those with solid tumors that have failed intervention with standard measures or those for which systemic therapy was considered ineffective. Patients must not be candidates for surgical resection. There have been eight patients treated (11 enrollments). Three patients were enrolled for ablation of different lesions. To date one subject achieved a complete response, five enrollments had stable disease, three developed progressive disease, one patient was cancelled and the last has not been analyzed. This trial continues to accrue patients.