Support of Yerkes National Primate Research Center

耶基斯国家灵长类研究中心的支持

• 批准号: 9072055
• 负责人: JONATHAN S LEWIN
• 金额: $ 1054.06万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9072055
• 关键词: Animal Housing; Basic Science; Behavioral; Behavioral Research; Biology; Biomedical Research; Breeding; Collaborations; Communities; Data; Development; Discipline; Disease; Ensure; Environment; Faculty; Funding; Genetic; Goals; Grant; Guidelines; Health; Housing; Human; Humanities; Immunology; Knowledge; Laboratory Research; Mental disorders; Microbiology; Mission; Neurologic; Neuropharmacology; Neurosciences; Pathology; Postdoctoral Fellow; Primates; Process; Publications; Reporting; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Role; Scientist; Services; Social Behavior; Strategic Planning; Translational Research; Transplantation; United States National Institutes of Health; Universities; Visit; animal facility; animal resource; base; cognitive neuroscience; graduate student; improved; innovation; laboratory facility; medical specialties; member; multidisciplinary; nonhuman primate; programs; public health relevance; research facility; training opportunity; undergraduate student

 DESCRIPTION (provided by applicant): This application seeks five years of continued support for the P51 Base Grant (OD 011132) for the Yerkes National Primate Research Center of Emory University. The overarching goals of Yerkes are to conduct a research program focused on scientific problems relevant to human health and the NIH mission by providing resource infrastructure and expertise in appropriate scientific and veterinary specialties and to ensure the Center's ability to serve as a resource to Core Scientists, as well as to scientists regionally, nationally and internationally. During the current reporting period (5/1/2011 to present), the Yerkes Center has recorded remarkable progress, as evidenced by numerous (>790) publications, construction of new animal facilities, including a state-of-the-art transplantation ad ABSL3 facility, and progressive expansion of its research funding base, even in the era of an extremely competitive NIH funding environment. In addition, the Yerkes Primate Center has maintained outstanding core research programs and provided resources and services to a broad multidisciplinary network of affiliate and collaborative investigators throughout the region and nation. These research programs, which involve the use of a variety of nonhuman primate species, are directed primarily toward four major research disciplines, representing the research divisions within the Yerkes Center: 1) Microbiology and Immunology; 2) Developmental and Cognitive Neuroscience, 3) Neuropharmacology and Neurologic Diseases and 4) Behavioral Neuroscience and Psychiatric Disorders. Also, through the Divisions of Animal Resources and Pathology, Yerkes provides support for outside investigators conducting research at the Yerkes Center, consistent with our ORIP-mandated role as a regional and national resource. Specific aims for the upcoming period of support include: 1) To carry out basic and translational research using nonhuman primates to expand knowledge, develop improved treatments, and advance cures that will benefit humanity; 2) To provide regional and national resources for data, consultative expertise, biologic materials, and specialized facilities useful in supporting nonhuman primate research; 3) To study basic nonhuman primate biology and improve nonhuman primate breeding, husbandry and genetic characterization to better serve the biomedical research community; and 4) To provide research and training opportunities involving nonhuman primates to graduate and undergraduate students, postdoctoral fellows, visiting scientists and faculty members. The pursuit of these aims will enhance the Center's ability to serve as an enabling resource to Core and Affiliate Scientists for the conduct of nonhuman primate research, all for the ultimate goal of advancing human health.

 描述(由申请者提供)：本申请寻求为埃默里大学耶克斯国家灵长类研究中心的P51基础补助金(OD 011132)提供五年的持续支持。Yerkes的首要目标是通过在适当的科学和兽医专业提供资源基础设施和专业知识，开展一项专注于与人类健康和NIH任务有关的科学问题的研究计划，并确保 中心作为核心科学家以及区域、国家和国际科学家的资源的能力。在本报告所述期间(2011年5月1日至今)，耶尔克斯中心取得了显著进展，其证据是：大量出版物(&gt；790)，建造新的动物设施，包括最先进的移植和ABSL3设施，并逐步扩大其研究资助基础，即使在竞争极其激烈的NIH资助环境中也是如此。此外，耶克斯灵长类研究中心一直保持着出色的核心研究项目，并为该地区和全国范围内广泛的多学科联合和协作调查人员网络提供资源和服务。这些研究项目涉及各种非人类灵长类物种的使用，主要针对四个主要研究学科，代表耶克斯中心的研究部门：1)微生物学和免疫学；2)发育和认知神经科学；3)神经药理学和神经疾病；4)行为神经科学和精神障碍。此外，通过动物资源和病理学部门，耶克斯为在耶克斯中心进行研究的外部调查人员提供支持，这与我们作为地区和国家资源的奥利普授权的角色是一致的。即将到来的支持期的具体目标包括：1)利用非人灵长类动物开展基础研究和转化研究，以扩大知识，开发改进的治疗方法，推进有益于人类的治疗方法；2)提供区域和国家资源，提供数据、咨询专业知识、生物材料和专门设施，用于支持非人灵长类动物研究；3)研究基础非人灵长类生物学，改进非人灵长类动物的繁殖、饲养和基因特征，以更好地服务于生物医学研究界；以及4)向本科生、博士后研究员、访问科学家和教职员工提供涉及非人类灵长类动物的研究和培训机会。对这些目标的追求将增强该中心的能力，使其成为核心和附属科学家进行非人类灵长类研究的有利资源，所有这些都是为了促进人类健康的最终目标。