MR GUIDED THERMAL ABLATION OF ABDOMINAL TUMORS

MR 引导腹部肿瘤热消融

• 批准号: 6276530
• 负责人: JONATHAN S LEWIN
• 金额: $ 1.83万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6276530
• 关键词: abdomen neoplasm; clinical research; human subject; human therapy evaluation; magnetic resonance imaging; metastasis; neoplasm /cancer thermotherapy

The objectives of this trial are: to describe the safety of Magnetic Resonance (MR) guided thermal ablation of soft tissue metastases and to describe the fraction of tumor necrosis that can be generated within tumors through thermal ablation using a radiofrequency (RF) generator as the heat source. Patients are only those with solid tumors that have failed intervention with standard measures or those for which systemic therapy was considered ineffective. Patients must not be candidates for surgical resection. There have been eight patients treated (11 enrollments). Three patients were enrolled for ablation of different lesions. To date one subject achieved a complete response, five enrollments had stable disease, three developed progressive disease, one patient was cancelled and the last has not been analyzed.

本试验的目的是：描述磁共振成像的安全性 软组织转移瘤的共振（MR）引导热消融， 描述肿瘤坏死的分数，可以产生内 使用射频（RF）发生器进行热消融治疗肿瘤 作为热源。 患者只有那些患有实体瘤， 标准措施或系统性措施干预失败 认为治疗无效。患者不得成为 手术切除 有8例患者接受了治疗（11例入组）。 三名患者 入组进行不同病变的消融。 去约会一个对象 达到完全缓解，5例入组患者病情稳定， 三名患者出现疾病进展，一名患者被取消治疗， 最后没有分析。