TRAINING PROGRAM IN MOLECULAR AND VIRAL ONCOLOGY

描述（申请人描述）：该计划的目标是提供高质量的博士前和博士后水平的培训，并为分子和病毒肿瘤学的研究和教学工作做好准备。申请人已经发展了一个多学科、多部门、17名研究人员组成的小组，他们在这些领域具有成熟的专业知识和研究兴趣。这些教员正在进行的研究项目包括研究致癌RNA和DNA病毒的遗传和复制，研究免疫反应的各种组成部分的成熟和发展以及在该系统中发生的肿瘤发生过程中的畸变，通过研究DNA结构和调节元件来调节基因表达，致癌基因在癌变中的作用及宿主免疫反应的分子研究。本提案的教员们拥有设备齐全、资金充足的实验室，可以进行所有阶段的研究。参与的教师认为，这代表了在分子和病毒肿瘤学领域提供优秀的博士前和博士后培训的良好环境。博士预科学员必须达到一个创新的多部门项目的入学和毕业标准，即“细胞和分子生物学（CMB）研究生项目”或高选择性的医学博士/博士学位。程序。参加分子和病毒肿瘤学课程的学生的具体要求包括参加病毒和分子肿瘤学的高级课程，以及期刊俱乐部和参加与该学科各个方面相关的研讨会。选定的课程、期刊俱乐部、研讨会和讨论小组也将由博士后学员参加。除了研究活动和课程外，培训方案还包括参加地方、区域和国家科学会议。博士生和博士后的培养将在全国范围内通过各种招聘计划进行招聘，并鼓励招募少数民族参与者。

DESCRIPTION (Applicant's Description): The objective of this program is to provide high quality training at the predoctoral and postdoctoral levels and to prepare outstanding individuals for careers in research and teaching in Molecular and Viral Oncology. The applicants have developed a multidisciplinary, multi-departmental, group of seventeen investigators with proven expertise and research interests in these areas. The ongoing research programs of these faculty members include the investigation of the genetics and replication of oncogenic RNA and DNA viruses, studies on the maturation and development of various components of the immune response and aberrations that occur during oncogenesis in this system, regulation of gene expression through studies on DNA structure and regulatory elements, the role of oncogenes in carcinogenesis and molecular studies of the host immune response. The faculty members in this proposal occupy laboratories that are well-equipped and well-funded for all phases of the research. The participating faculty believes that this represents an excellent environment for providing outstanding predoctoral and postdoctoral training in the area of Molecular and Viral Oncology. Predoctoral trainees are required to meet the admission and graduation standards of an innovative multi- departmental program entitled the "Cellular and Molecular Biology (CMB) Graduate Program" or a highly selective M.D./Ph.D. program. Specific requirements for students enrolled in the Molecular and Viral Oncology Program include participation in an advanced level course in viral and molecular oncology as well as journal clubs and attendance at seminars relevant to the various aspects of this discipline. Selected course offerings, journal clubs, seminars, and discussion groups will be attended by postdoctoral trainees also. In addition to research activities and courses the training program includes participation in local, regional and national scientific meetings. Recruitment of both predoctoral and postdoctoral trainees will be at the national level through a variety of recruitment programs and will encourage recruitment of minority participants.