课题基金 / 基金详情

RELEVANCE OF CHEMICALLY INDUCED FORESTOMACH NEOPLASMS IN B6C3F1 MOUSE

RELEVANCE OF CHEMICALLY INDUCED FORESTOMACH NEOPLASMS IN B6C3F1 MOUSE
B6C3F1 小鼠化学诱发前胃肿瘤的相关性
批准号：
6162143
负责人：
H L HONG
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6162143
关键词：
animal genetic material tag carcinogen testing chemical carcinogen chemical carcinogenesis cobalt laboratory mouse mutagen testing mutagens neoplasm /cancer genetics point mutation protooncogene stomach neoplasms sulfates tumor suppressor genes

项目摘要

项目成果

H L HONG的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Summary of Work: Cobalt sulfate induced a higher incidence of alveolar/bronchiolar adenomas and carcinomas in male and female mice exposed to various concentrations of cobalt sulfate compared to controls. DNA samples from lung neoplasms were sequenced for point mutations in the K-ras gene. Unique point mutations were detected in K-ras exon 2. Future work on this project includes determining the mechanism for the unique mutations and characterizing genetic alterations in potential tumor suppressor genes which may be relevant to human exposure. The findings for the first part of these studies were presented to the Peer Review Board in December 1996.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
RAS ONCOGENE MUTATIONS IN LIVER NEOPLASMS OF B6C3F1 MICE ESPOSED TO TFE
EFFECTS OF GLYCOL ETHERS ON BONE MARROW PARAMETERS
EFFECTS OF GLYCOL ETHERS ON BONE MARROW PARAMETERS
EFFECTS OF GLYCOL ETHERS ON BONE MARROW PARAMETERS
海外基金