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MYELOTOXICITY IN MICE CAUSED BY DRINKING MIXTURE OF GROUNDWATER CONTAMINANTS

MYELOTOXICITY IN MICE CAUSED BY DRINKING MIXTURE OF GROUNDWATER CONTAMINANTS
饮用地下水污染物混合物引起的小鼠骨髓毒性
批准号:
3918652
负责人:
H L HONG
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
Concern over the potential adverse health effects of chemically contaminated groundwater has existed for many years. In the present studies bone marrow parameters were monitored in female B6C3F1 mice exposed to a chemical mixture in drinking water for 17 days or up to 32 weeks. The mixture consisted of 25 common groundwater contaminants frequently found near toxic waste dumps, as determined by EPA surveys. The purpose of these experiments were to compare the hematopoisis among the different time courses of exposure and to determine whether residual damage could be demonstrated by subsequent radiations at a time when hematopoietic stem cells sustained injury or nearly recovered.
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