APEX: ADIPOSITY PREVENTION BY EXERCISE IN BLACK GIRLS

APEX：黑人女孩通过运动预防肥胖

• 批准号: 6127952
• 负责人: Bernard Gutin
• 金额: $ 63.42万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6127952
• 关键词: African American; aerobic exercise; behavioral /social science research tag; body composition; cardiovascular function; clinical research; diet; disease /disorder prevention /control; elementary school; female; health behavior; human puberty; human subject; human therapy evaluation; longitudinal human study; middle childhood (6-11); nutrition related tag; obesity; physical fitness; self concept

DESCRIPTION: (Adapted from Investigator's Abstract) The long term objective of this research is to reduce the epidemic of child obesity that is afflicting U.S. society. Obese children who engage in vigorous exercise programs show beneficial effects on total body percent fat (percent BF) and visceral adipose tissue (VAT); however, little is known about how to prevent accretion of total body or visceral adiposity in high risk youths, such as African-American (AA) females. The primary aim is to test the hypothesis that a one year afternoon exercise program will reduce accretion of general and visceral adiposity in AA girls. The design will involve randomization of AA girls, eight to 10 years of age (n=200) into intervention or control groups. After one year, the groups will be compared to test the primary hypothesis. Then the girls will switch group assignments for the next year. The pattern of data over the three time points will show what happens over a two year period in which the youths are, or are not, involved in the exercise program. The measurements will include: (1) percent BF with dual-energy x-ray absorptiometry; (2) VAT with magnetic resonance imaging; (3) CV fitness with a multi-stage treadmill test; (4) CVD risk factors (i.e., the ratio of total to high density lipoprotein cholesterol, insulin, systolic blood pressure, and fibrinogen); (5) free-living exercise and diet; (6) psychosocial variables (i.e., self-efficacy and self-concept); C7) sexual maturation; (8) anthropometric measures. The exercise program will be implemented in neighborhood schools for 90 minutes each weekday afternoon. Transportation will be provided if needed. Sessions will include motor skill instruction and aerobic exercises. The investigators state that this project has important health implications for two reasons, as follow. (1) They state that there is a dearth of information concerning the effects of exercise interventions in school and community settings. (2) They further state that if this project shows that an afternoon exercise program reduces accretion of general and visceral adiposity and has a favorable impact on fitness and health in a population that is at high risk of obesity, then schools may be encouraged to implement similar interventions to prevent juvenile obesity and associated health problems.

描述：（改编自研究者摘要）长期目标 这项研究旨在减少困扰儿童的肥胖症的流行 美国社会。参加剧烈运动项目的肥胖儿童表现出 对全身脂肪百分比（BF 百分比）和内脏脂肪的有益影响 组织（增值税）；然而，人们对如何防止总量增加知之甚少。 高危青少年的身体或内脏肥胖，例如非洲裔美国人 (AA) 女性。主要目的是检验一年下午的假设 运动计划将减少 AA 中全身和内脏肥胖的增加 女孩们。该设计将涉及 AA 女孩的随机化，八到 10 年的 年龄（n=200）分为干预组或对照组。一年后，各组 将进行比较以检验主要假设。然后女生就换了 明年的小组作业。三个时间段的数据规律 积分将显示青少年在两年内发生的情况， 或没有参与锻炼计划。测量将包括： (1)双能X射线吸收法测定BF百分比； (2)增值税带磁 共振成像； (3) 通过多阶段跑步机测试进行 CV 适应性测试； (4)化学气相沉积 危险因素（即总胆固醇与高密度脂蛋白胆固醇的比率， 胰岛素、收缩压和纤维蛋白原）； (5) 自由生活锻炼 饮食; (6) 社会心理变量（即自我效能和自我概念）； C7) 性成熟； (8)人体测量。锻炼计划将是 每个工作日下午在社区学校实施 90 分钟。 如果需要，我们将提供交通服务。课程将包括运动技能 指导和有氧运动。调查人员表示，该项目 由于以下两个原因，它具有重要的健康影响。 (1) 他们指出 缺乏有关运动效果的信息 对学校和社区环境的干预。 (2) 他们进一步指出，如果 该项目表明，下午的锻炼计划可以减少 全身和内脏肥胖，对健身和健康有有利影响 在肥胖风险高的人群中，可以鼓励学校 实施类似的干预措施，预防青少年肥胖及相关疾病 健康问题。