ADHD AND EXECUTIVE FUNCTIONS--RELATION TO LEARNING DISABILITIES

ADHD 和执行功能——与学习障碍的关系

• 批准号: 6241120
• 负责人: BRUCE F PENNINGTON
• 金额: $ 17.1万
• 依托单位: UNIVERSITY OF COLORADO
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-01 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6241120
• 关键词: Turner's syndrome; adolescence (12-20); attention deficit disorder; behavioral /social science research tag; clinical research; comorbidity; family genetics; female; fragile X syndromes; genetic disorder diagnosis; human subject; interview; learning disorders; medical complication; middle childhood (6-11); neurofibromatosis; neuropsychological tests; phenylketonurias; psychomotor function; reading disorder; statistics /biometry; twin /multiplet

The overall goal of the proposed research is to use converging methods to better understand the causal relation between RD and its psychiatric correlates particularly ADHD. The specific goals of the proposed research are: 1. To administer measures of attention deficit hyperactivity disorder (ADHD) and executive functions (EFs) to three different populations; a) 50 pairs of MZ and 50 pairs of DZ twins in which at least one member of each pair is reading disabled (RD); b) an independent sample of 50 pairs of MZ and 50 pairs of DZ twins in which at least one member of each pair manifests symptoms of ADHD; and c) a comparison group of 50 pairs of MZ and 50 pairs of DZ twins with no school history of learning disabilities (LDs) or ADHD. 2. To perform a genetic linkage study to identify one or more quantitative trait loci (QTLs) influencing ADHD. 3. To test competing explanations for the association between RD and ADHD using genetic and neuropsychological analyses. 4. To examine the rates and etiology of other psychiatric correlates of RD and ADHD.

提出的研究的总体目标是使用收敛的方法