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REDUCED FOLATE METABOLITES OF LEUCOVORIN

REDUCED FOLATE METABOLITES OF LEUCOVORIN
减少亚叶酸的叶酸代谢物
批准号:
6280086
负责人:
PERRY VICTOR HALUSHKA
金额:
$2.73万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-12-01 至 1998-11-30

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中文摘要
翻译
亚叶酸钙还原代谢的研究进展 叶酸代谢物已在正常人体内成功进行 志愿者。这项研究试图确定时间进程和模式 重复口服后还原型叶酸代谢物的蓄积 给正常志愿者服用叶酸,并比较这些 结果与先前对亚叶酸和单剂量叶酸的研究结果一致。
英文摘要
Previous investigations of the metabolism of leucovorin to its reduced folate metabolites have been successfully carried out in normal volunteers. This study seeks to determine the time course and pattern of accumulation of reduced folate metabolites after repetitive oral administration of folic acid to normal volunteers, and to compare these results to previous studies of leucovorin and single-dose folic acid.
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