DEVELOPMENT OF SECOND GENERATION FLUORESCENCE EEM SYSTEM

第二代荧光EEM系统的研制

• 批准号: 6281760
• 负责人: RAMASAMY MANOHARAN
• 金额: $ 2.27万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-01 至 1999-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281760
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; biomedical resource; building /facility design /renovation; clinical research; human tissue; spectrometry; technology /technique; women's health

We are continuously improving our current in vivo EEM system which can collect 10 fluorescence spectra excited with 10 different light sources and diffuse reflectance spectra from the same tissue in less than a second. The improvements are being carried out in three areas: (a) use of stepper motor to access invidual excitation wavelengths when needed and also accumulate multi-pulse fluorescence data, (b) use of compact high sensitive CCD detector especially important in collecting data from cancerous tissue sites which are inherently weaker emitters, (c) simply the electronics, make it portable and easy to use.

我们正在不断改进我们目前的体内EEM系统， 可以收集10种不同光激发的10个荧光光谱 源和漫反射光谱从同一组织在更少的 一秒钟。 这些改进工作在三个方面进行： (a)使用步进电机访问各个激发波长 并且还累积多脉冲荧光数据，（B）使用 紧凑型高灵敏度CCD探测器， 从癌症组织部位收集数据， 较弱的发射器，（c）简单的电子设备，使其便携和容易 使用.