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FLUORESCENCE EEM SPECTROSCOPY FOR DETECTION OF DYSPLASIA IN EPITHELIAL TISSUES

FLUORESCENCE EEM SPECTROSCOPY FOR DETECTION OF DYSPLASIA IN EPITHELIAL TISSUES
用于检测上皮组织发育不良的荧光 EEM 光谱
批准号：
6314212
负责人：
RAMASAMY MANOHARAN
金额：
$1.38万
依托单位：
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-06-01 至 2001-05-31
来源：
https://reporter.nih.gov/project-details/6314212
关键词：
biomedical equipment development biomedical resource human tissue oral pharyngeal technology /technique urinary tract

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中文摘要
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英文摘要
We have developed in vivo EEM system which can collect 10 fluorescence spectra excited with 10 different light sources and diffuse reflectance spectra from the same tissue in less than a second. This system is currently being used to study precancerous changes in Barrett's esophagus and colon. So far we have examined nearly 55 patients undergoing surveillance for dysplasia in Barrett's esophagus. The system is also being used at the Brigham and Women's Hospital for studying adenomatous polyps and dysplasia in colon. The wealth of fluorescence information provided by rapid EEM system is being analyzed using model based approach and principal component analysis approach.
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CHARACTERIZATION OF OPTICAL FIBER PROBES FOR IN VIVO RAMAN SPECTROSCOPY
DEVELOPMENT OF SECOND GENERATION FLUORESCENCE EEM SYSTEM
COMBINED RAMAN & FLUORESCENCE METHODS FOR BREAST CANCER DETECTION & IMAGING
FLUORESCENCE EEM SPECTROSCOPY FOR DETECTION OF DYSPLASIA IN EPITHELIAL TISSUES
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