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DEVELOPMENT OF SECOND GENERATION FLUORESCENCE EEM SYSTEM

DEVELOPMENT OF SECOND GENERATION FLUORESCENCE EEM SYSTEM
第二代荧光EEM系统的研制
批准号：
6314211
负责人：
RAMASAMY MANOHARAN
金额：
$1.38万
依托单位：
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-06-01 至 2001-05-31
来源：
https://reporter.nih.gov/project-details/6314211
关键词：
bioengineering /biomedical engineering biomedical equipment development biomedical resource building /facility design /renovation clinical research human tissue spectrometry technology /technique women's health

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中文摘要
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英文摘要
We are continuously improving our current in vivo EEM system which can collect 10 fluorescence spectra excited with 10 different light sources and diffuse reflectance spectra from the same tissue in less than a second. The improvements are being carried out in three areas: (a) use of stepper motor to access invidual excitation wavelengths when needed and also accumulate multi-pulse fluorescence data, (b) use of compact high sensitive CCD detector especially important in collecting data from cancerous tissue sites which are inherently weaker emitters, (c) simply the electronics, make it portable and easy to use.
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CHARACTERIZATION OF OPTICAL FIBER PROBES FOR IN VIVO RAMAN SPECTROSCOPY
DEVELOPMENT OF SECOND GENERATION FLUORESCENCE EEM SYSTEM
COMBINED RAMAN & FLUORESCENCE METHODS FOR BREAST CANCER DETECTION & IMAGING
FLUORESCENCE EEM SPECTROSCOPY FOR DETECTION OF DYSPLASIA IN EPITHELIAL TISSUES