CORE--STATISTICAL

统计核心的总体目标是：（1）确保 数据及其对项目调查人员的访问;（2）确保适当的 假设检验和假设生成的数据分析;以及（3） 以确保每个项目和核心中收集的数据最佳 用于特定项目和跨项目分析。具体 统计核心的目标是：（1）确保高质量的数据， （2）协助调查人员进行调查， 在合作和咨询的基础上分析数据;（3） 促进项目和核心之间的数据和想法交流;（4） 协助调查人员制定可检验的假设， 假设涉及多个项目的数据;（5）协助项目 研究人员在进行假设检验时， （6）尽可能发展“强大”的认知能力 最适合诊断AD（和其他痴呆症）的测试规范， 识别临床前个体中的记忆障碍;以及（7） 开发方法来区分神经心理学，神经学， AD早期表现出的神经病理学缺陷来自于 正常老化。

The overall goals of the Statistical Core are to: (1) To insure quality of data and its accessibility to project investigators; (2) To insure proper analysis of data for hypothesis testing and hypothesis generation; and (3) to insure that the data collected in each project and core are optimally utilized for both project specific and cross-project analyses. Specific aims of the Statistical Core are: (1) To insure a high quality of data for each of the projects and Cores; (2) To assist investigators in the analyses of the data on both a collaborative and consultive basis; (3) To facilitate the exchange of data and ideas among projects and cores; (4) To assist investigators in framing testable hypothesis and in generating hypothesis involving data from multiple projects; (5) To assist project investigators in conducting hypothesis testing using both cross-sectional and longitudinal data whenever possible; (6) To develop 'robust' cognitive test norms that are optimal for diagnosing AD (and other dementia) and identifying memory impairment in preclinical individuals; and (7) To develop methods to distinguish neuropsychological, neurologic, and neuropathologic deficits exhibited in early AD from changes which occur normal aging.