A new target for antidepressant treatment: microglia mediated neuroinflammation

抑郁症是澳大利亚非致命疾病负担的主要原因。不幸的是，目前的抗抑郁药物并不能提供足够的缓解效果，人们普遍认为我们需要开发更有效的治疗方法。我们最近证明，一种减少大脑炎症的药物也可以减少抑郁症样症状。该项目旨在扩展这些极其有希望的发现，希望开发出新一代更有效的抗抑郁药。

Depression is the leading cause of non-fatal disease burden in Australia. Unfortunately, current antidepressants do not provide adequate levels of relief and it is accepted that we need to develop more effective treatments. We have recently shown that a drug that reduces inflammation in the brain also reduces depression-like symptoms. This project aims to extend upon these extremely promising findings, in the hope of developing a new and more effective generation of antidepressants.