CARDIOVASCULAR SCIENCES TRAINING GRANT

心血管科学培训补助金

• 批准号: 6343353
• 负责人: HARRY A FOZZARD
• 金额: $ 51.5万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-07-01 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6343353
• 关键词: CARDIOVASCULAR; SCIENCES; TRAINING; GRANT

This competing continuation application for a Cardiovascular Sciences Training Grant is an important component of the established cardiovascular research program at the University of Chicago. The long- term objective of this training program is to train pre- and post- doctoral MD and PhD fellows for independent basic research careers in cellular and molecular cardiovascular biology. This application is structured around the principle that a successful modern cardiovascular biology training program must o beyond the traditional boundaries of cardiac physiology and pharmacology to include diverse areas of basic molecular and cellular investigation; more specifically, studies of gene expression, transgenic models of human disease, novel methods of somatic gene therapy, and vascular and transplantation biology. Accordingly our training program is interdivisional and interdepartmental involving 17 training faculty from the departments of Medicine, Pathology, Pharmacology/Physiology, Immunology, and the HHMI. The cohesiveness of the training program derives from the fact that the preceptors are organized into four related collaborative groups with programmatic interests in (i) Gene Expression and gene therapy in the cardiovascular system, (ii) cellular and molecular electrophysiology, (iii) vascular biology, and (iv) transplantation biology. The training program is directed by Jeffrey M. Leiden, MD, PhD the Frederick H. Rawson Professor of Medicine and Chief of the Section of Cardiology. Direction of the program is overseen by an executive committee comprised of senior scientists at the University of Chicago. The success of the program over the last four year is evidenced by the fact that it has provided training support for 7 outstanding pre-doctoral and 21 post-doctoral fellows who have published 45 manuscripts in outstanding peer reviewed journals since 1994. Funding is requested for 9 MD and PhD post-doctoral fellows per year who are performing full time basic research. One of the important features of the training program is the fact that PhD and MD post-doctoral fellows are trained together in collaborative environments by preceptors who hold either MD or PhD degrees or both. To interest younger MD and PhD students in the cardiovascular sciences funding is also requested for three post-doctoral fellows. The training program will include individually tailored formal graduate coursework, and participation in a biweekly research seminar and journal club. Fellows will receive most of their training in the research laboratories of their preceptors. Upon completion of the training program post-doctoral fellows should be able to function as independent investigators within an academic basic science and/or medical school environment.

心血管科学培训补助金的竞争性继续申请是芝加哥大学既定心血管研究计划的重要组成部分。该培训项目的长期目标是培养博士前和博士后MD和博士研究员，从事细胞和分子心血管生物学的独立基础研究。该应用程序是围绕一个成功的现代心血管生物学培训计划必须超越心脏生理学和药理学的传统界限，包括基础分子和细胞研究的不同领域，更具体地说，基因表达，人类疾病的转基因模型，体细胞基因治疗的新方法，以及血管和移植生物学的研究。因此，我们的培训计划是跨部门和跨部门的，涉及来自医学，病理学，药理学/生理学，免疫学和HHMI部门的17名培训教师。培训计划的凝聚力来自于这样一个事实，即导师被组织成四个相关的合作小组，其计划兴趣是（i）心血管系统中的基因表达和基因治疗，（ii）细胞和分子电生理学，（iii）血管生物学和（iv）移植生物学。该培训项目由杰弗里M。莱顿，医学博士，博士弗雷德里克H。医学罗森教授和心脏科主任。该计划的方向由芝加哥大学的高级科学家组成的执行委员会监督。该计划在过去四年中的成功证明了这一事实，即它为自1994年以来在优秀的同行评审期刊上发表了45篇论文的7名优秀博士前和21名博士后研究员提供了培训支持。每年为9名从事全职基础研究的博士和博士博士后研究员提供资金。培训计划的一个重要特点是，博士和MD博士后研究员在合作环境中由拥有MD或博士学位或两者的导师共同培训。为了吸引年轻的医学博士和博士生对心血管科学的兴趣，还要求为三名博士后研究员提供资金。培训计划将包括单独定制的正式研究生课程，以及参加每两周一次的研究研讨会和期刊俱乐部。研究员将在导师的研究实验室接受大部分培训。完成培训计划后，博士后研究员应能够在学术基础科学和/或医学院环境中担任独立调查员。