STRUCTURAL CHARACTERIZATION OF NICOTINIC ACETYLCHOLINE RECEPTOR

烟碱乙酰胆碱受体是最好的特征 配体门控离子通道，一个超家族的成员， 神经递质受体也包括GABA受体， 血清素和甘氨酸。 它在调解沟通中很重要 神经元之间。 许多心理过程和障碍源于正常的 功能和缺陷，在这个家庭的受体，和结构 这种受体是设计新药的关键第一步， 大药厂 我们将获得更多关于 膜蛋白、离子通道和糖蛋白。

The nicotinic acetylcholine receptor is the best-characterized ligand-gated ion channel, a member of a superfamily of neurotransmitter receptors that also includes receptors for GABA, serotonin and glycine. It is important in mediating communication between neurons. Many mental processes and disorders stem from normal function and defects in this family of receptors, and the structure of this receptor is a key first step toward the design of new drugs and pharmaceuticals. We stand to gain much insight about the structure of membrane proteins, ion channels, and glycoproteins from such a study.