An universal recipient for protein production in eggs

描述（由申请人提供）：迄今为止，嵌合鸡是由 将胚盘细胞或胚胎干细胞注入X期胚胎 （受体），但嵌合体的频率和水平是可变的， 不可预测我们计划开发一个贡献最小的普遍接受者， 因此供体来源的细胞对所得嵌合体的贡献是恒定的 高和可预测的。体细胞嵌合体可用于生产生物制药 一旦嵌合体开始产卵， 将编码生物药物蛋白质的基因传递给下一代。 拟议商业应用：不可用

DESCRIPTION (provided by applicant): To date, chimeric chickens are made by injecting blastodermal cells or embryonic stem cells into the stage X embryo (recipient), but the frequency and the level of chimerism is variable and unpredictable. We plan to develop a universal recipient that contributes minimally, so that the contribution of donor derived cells to the resulting chimera is constantly high and predictable. Somatic chimeras can be used to produce biopharmaceutical proteins in eggs as soon as the chimeras commence laying and before they transmit the gene encoding the biopharmaceutical protein to the next generation. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE