MOUSE PATHOBIOLOGY: MODELS OF HUMAN DISEASE

小鼠病理学：人类疾病模型

• 批准号: 6622641
• 负责人: THOMAS J ROSOL
• 金额: $ 24.78万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6622641
• 关键词: MOUSE; PATHOBIOLOGY; MODELS; HUMAN; DISEASE

DESCRIPTION (Provided by applicant): The OSU Mouse Pathobiology training program is a four-year program designed to produce veterinary scientists capable of conducting independent and collaborative research using mouse models of human disease. Trainees will be selected from motivated and talented D.V.M. or D.V.M., Ph.D. candidates who are committed to careers in research. Trainees will complete one year of specialty education in veterinary pathology, clinical pathology, microbiology, or laboratory animal medicine that will include a three month rotation through the Laboratory Animal Program. The first year will be funded by the Department of Veterinary Biosciences. Then the T32 training program will require three years during which trainees will complete independent research projects within a training faculty's laboratory. Trainees without a Ph.D. degree will pursue a Ph.D. in Comparative and Experimental Pathobiology in the Department of Veterinary Biosciences. The research projects will focus on using mouse models to investigate the pathophysiology of significant human diseases. The training faculty (24 members) have focused research excellence in comparative cancer medicine, infectious diseases, immunology, and development of genetically altered mouse models of human disease. All training faculty use experimental mouse models of human disease in their work. The 24 training faculty represent a diverse spectrum of investigators in veterinary biosciences, internal medicine, medical biochemistry and physiology, cancer genetics, mouse genetics, surgery, molecular biology, and oral biology that have developed a network of collaborative interactions within The Ohio State University Health Sciences Center (consisting of seven colleges). The training faculty represent the Colleges of Veterinary Medicine, Medicine, Biologic Sciences, and Dentistry. The OSU Comprehensive Cancer Center (including its core services), James Cancer Hospital and Solove Research Institute, and transgenic cores of the Neurobiotechnology Center and Children's Hospital are organizations at the OSU that will facilitate the research programs and training faculty interaction. Selected formal courses will be chosen for trainees based on their needs and goals. Completion of the program will enable trainees to develop the skills necessary to design and conduct in vivo experiments and serve as resource persons in academic or industrial institutions to facilitate research projects using mouse models of human disease.

描述（由申请人提供）：OSU小鼠病理学培训 该计划是一个为期四年的计划，旨在培养兽医科学家 能够使用鼠标进行独立和协作研究 人类疾病的模型。学员将从积极主动和有才华的 D.V.M.或DVM，博士致力于研究事业的候选人。 受训人员将完成一年的兽医专业教育 病理学、临床病理学、微生物学或实验动物医学 这将包括在实验室动物中进行为期三个月的轮换 程序. 第一年将由兽医局资助。 生物科学。 那么T32训练计划将需要三年的时间， 哪些学员将在培训期间完成独立的研究项目 教师的实验室 没有博士学位的学员学位将继续攻读博士学位。在 兽医系比较与实验病理学 生物科学。 研究项目将集中在使用小鼠模型， 研究重大人类疾病的病理生理学。 培训 教师（24名成员）专注于比较癌症的卓越研究 医学、传染病、免疫学和遗传学的发展 改变人类疾病的小鼠模型。 所有培训教师都使用实验 人类疾病的小鼠模型。 24培训学院 代表了兽医生物科学领域的各种研究人员， 内科学、医学生物化学和生理学、癌症遗传学、小鼠 遗传学、外科学、分子生物学和口腔生物学， 俄亥俄州州立大学卫生部内的协作互动网络 科学中心（由七个学院组成）。 培训学院 代表兽医学院，医学，生物科学， 和牙科。 OSU综合癌症中心（包括其核心 服务），詹姆斯癌症医院和Solove研究所，和转基因 神经生物技术中心和儿童医院的核心是 组织在俄勒冈州立大学，将促进研究计划， 培训教师互动。 选定的正式课程将被选择， 学员根据自己的需要和目标。 该计划的完成将 使受训者能够发展必要的技能，设计和进行体内 实验，并担任学术或工业界的资源人员 机构促进研究项目使用小鼠模型的人类 疾病