Longitudinal analysis of the effects of lifelong physical activity on muscle and immune ageing

终身体力活动对肌肉和免疫衰老影响的纵向分析

• 批准号: 2278262
• 金额: --
• 依托单位: University of Birmingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2278262
• 关键词: Longitudinal; analysis; effects; lifelong; physical

We previously undertook a cross sectional study to determine the effects of ageing and inactivity on immune function. However, cross sectional studies have an inherent limitation; thus this PhD studentship will resample this cohort of cyclists (8 years since initial investigation) and compare the trajectory of muscle and immune ageing with a sedentary cohort that had also been originally sampled in 2012. Secondly, this PhD studentship will also determine potential mechanisms involved in any improved trajectory.

我们之前进行了一项横断面研究，以确定衰老和不活动对免疫功能的影响。然而，横断面研究有其固有的局限性；因此，这个博士研究生将重新对这群骑自行车的人（自最初调查以来已有8年）进行抽样，并将肌肉和免疫老化的轨迹与2012年首次抽样的久坐人群进行比较。其次，这个博士学位也将确定任何改进轨迹所涉及的潜在机制。