CORE--TISSUE RESEARCH AND PATHOLGOGY SERVICES

组织和研究病理服务(TARPS)是一个新提出的共享设施，用于为需要匹兹堡大学医学中心(UPMC)患者的组织材料的UPCI研究项目提供中央支持。不良资产救助计划的主要目标是(1)提供一种机制，简化和精简研究组织的积累和支付过程；(2)提供有效的研究病理学支持服务。组织 不良资产救助计划的应计和支出职能自1991年以来一直作为一个小型服务机构存在，重点放在泌尿生殖系癌症上。该资源在过去5年中大幅扩大，现在从患有各种癌症的患者那里采购和支付组织材料，并为主要研究项目提供支持，如HMG卓越研究专门计划(Spoor)、早期疾病研究网络(EDRN)相关 研究努力，以及其他几个癌症研究项目。 TARP提供的服务包括(1)组织和生物标本采购服务，(2)研究组织学服务，(3)带注释的临床数据，以及(4)组织微阵列(TMA)设施。未来的努力包括开发实时绘制肿瘤分子轮廓的程序。TARPS计划将其已有的针对前列腺癌和头颈部癌等癌症的基础设施的开发扩展到其他领域，如胃肠道和胰腺癌、血液系统恶性肿瘤和黑色素瘤。

The Tissue and Research Pathology Services (TARPS) is a newly proposed shared facility that serves as the central support for UPCI research programs needing tissue materials from patients at the University of Pittsburgh Medical Center (UPMC). The main objectives of TARPS are (1) to provide a mechanism to simplify and streamline the process of research tissue accrual and disbursement and (2) to provide efficient research pathology support services. The tissue accrual and disbursement function of TARPS has been in existence since 1991 as a small service facility, with a focus on genitourinary cancers. The resource has substantially expanded in the last 5 years and now procures and disburses tissue materials from patients with a diverse array of cancers, and provides support to major research projects such as the hmg Specialized Program Of Research Excellence (SPORE), Early Disease Research Network (EDRN)-related research efforts, and several other cancer research programs. Services provided by TARPS include (1) tissue and biological specimen procurement services, (2) research histology services, (3) annotated clinical data, and (4) the Tissue Micro-Array (TMA) facilities. Future efforts include development of procedures to molecularly profile tumors on a real time basis. TARPS plans to extend the development of its infrastructure already in place for cancers such as prostate and head and neck cmacers, to other areas such as gastrointestinal and pancreatic cancers, hematologic malignancies, and melanoma.