Center for Molecular & Cellular Studies of Ped Disease

描述（由申请人提供）：我们缺乏对儿科疾病的基本过程及其适当治疗的了解，给儿童及其家庭造成了沉重的负担。 我们的CHRCDA计划将通过培训和指导年轻的儿科研究人员来解决这个问题。 主要研究者将是Michael M.博士。Frank，儿科系主任，在培训和指导方面有着长期成功的职业生涯。 该计划的日常方向将由计划主任，博士页A。W.安德森，儿科研究副主席。 Dr. Delbert R. Wigfall，儿科副教授，副院长和杜克机构多元文化资源中心主任，将是我们的少数民族招聘顾问。 该计划将有两个委员会。 弗兰克，是由我们的部门和机构的成员谁是经验丰富的研究人员和导师在我们的机构领导角色。 一个小组委员会将对潜在的受训人员进行评估和排名。 从代表性不足的少数民族中招募学员将是我们计划的重点。 弗兰克医生会挑选学员 委员会将定期与学员和导师面谈。 他们将与弗兰克博士和安德森博士合作，采取任何必要的行动，支持受训人员通过该计划取得进展。 外部咨询委员会由来自美国各地的国际公认的科学家和儿科医生组成，将每年审查计划目标的实现情况，受训人员的进展情况，并向主要研究者提供建议。 第一年将招收四名受训人员，每年资助四名。 培训期为2至5年。 学员将把75%以上的时间用于培训计划。 导师将根据他们在指导方面的成功、他们研究的儿科相关性、领导作用和NIH资金来选择。 学员将被要求参加课程的研究，赠款和手稿写作的负责任的行为，以及核心课程，包括统计学介绍，遗传数据分析，和人类疾病的分子遗传学。 学员将被要求进行口头报告，以发展他们的沟通技巧。 我们致力于招聘这些实习生到我们的系。 我们以前在培训和发展初级研究人员的科学事业方面的成功支持了CHRCDA培养成功的学术儿科科学家的长期目标。

DESCRIPTION (provided by applicant): Our lack of understanding of the processes underlying pediatric illnesses and their appropriate therapy inflicts a heavy burden on children and their families. Our CHRCDA program will address this issue through training and mentoring young pediatric investigators. The Principal Investigator will be Dr. Michael M. Frank, Chair of the Department of Pediatrics, who has had a long successful career in training and mentoring. The day-to-day direction of the program will be provided by the Program Director, Dr. Page A. W. Anderson, Vice Chair of Research for the Department of Pediatrics. Dr. Delbert R. Wigfall, Associate Professor of Pediatrics, Associate Dean and Director of the Duke Institutional Multicultural Resource Center, will be our Minority Recruitment Advisor. The program will have two committees. The Internal Advisory Committee, chaired by Dr. Frank, is made up of members of our department and institution who are experienced investigators and mentors with leadership roles in our Institution. A subcommittee will assess and rank potential trainees. Recruitment of trainees from under-represented minorities will be a focus of our program. Dr. Frank will select the trainees. The Committee will interview the trainees and mentors on a regular basis. They, in concert with Drs. Frank and Anderson, will initiate any needed actions to support the progress of the trainees through the program. The External Advisory Board, made up of internationally recognized scientists and pediatricians from across the United States, will review on an annual basis the accomplishment of the program goals, the progress of the trainees and advise the Principal Investigator. Four trainees will be admitted the first year and four supported each year of the program. The training period will last from two to five years. The trainees' will dedicate over 75% of their time to the training program. The mentors will be selected based on their success in mentoring, the pediatric relevance of their research, leadership roles, and NIH funding. The trainees will be required to take courses in Responsible Conduct of Research, grant and manuscript writing, and core courses that include an Introduction to Statistics, Analysis of Genetic Data, and Molecular Genetics of Human Disease. The trainees will be required to give oral presentations to develop their communication skills. We are committed to recruiting these trainees to our department faculty. Our previous success in training and developing the scientific careers of junior investigators supports the long-term goal of this CHRCDA to develop successful academic pediatric scientists.