Center for Molecular & Cellular Studies of Ped Disease

描述（由申请人提供）：我们缺乏对儿科疾病的潜在过程及其适当治疗的理解，给儿童及其家庭带来了沉重的负担。我们的CHRCDA项目将通过培训和指导年轻的儿科研究者来解决这个问题。首席研究员将是儿科系主任Michael M. Frank博士，他在培训和指导方面有着长期成功的职业生涯。该项目的日常指导将由项目主任，儿科研究副主任Page A. W. Anderson博士提供。Dr. Delbert R. Wigfall，儿科副教授，杜克大学多元文化资源中心副院长和主任，将是我们的少数民族招生顾问。该项目将设立两个委员会。内部谘询委员会由Frank博士担任主席，成员均为本署及研究所经验丰富的调查人员及导师，在本所担当领导角色。一个小组委员会将对潜在的学员进行评估和排名。从代表性不足的少数民族招募学员将是我们项目的重点。弗兰克博士将挑选实习生。委员会将定期与受训人员和导师面谈。他们与dr。弗兰克和安德森将采取任何必要的行动来支持受训人员在项目中的进步。外部咨询委员会由来自美国各地的国际知名科学家和儿科医生组成，将每年审查项目目标的完成情况、受训者的进展情况，并向首席研究员提供建议。该项目第一年将招收四名学员，每年将支持四名学员。培训期为二至五年。学员将投入超过75%的时间在培训项目上。导师将根据他们在指导方面的成功、他们的研究与儿科的相关性、领导角色和NIH的资助来选择。受训者将被要求学习负责任的研究行为、拨款和手稿写作等课程，以及包括统计学概论、遗传数据分析和人类疾病分子遗传学在内的核心课程。学员将被要求进行口头陈述，以发展他们的沟通技巧。我们承诺将这些受训者招募到我们系的教职员工中。我们之前在培训和发展初级研究人员的科学事业方面的成功支持了CHRCDA培养成功的学术儿科科学家的长期目标。

DESCRIPTION (provided by applicant): Our lack of understanding of the processes underlying pediatric illnesses and their appropriate therapy inflicts a heavy burden on children and their families. Our CHRCDA program will address this issue through training and mentoring young pediatric investigators. The Principal Investigator will be Dr. Michael M. Frank, Chair of the Department of Pediatrics, who has had a long successful career in training and mentoring. The day-to-day direction of the program will be provided by the Program Director, Dr. Page A. W. Anderson, Vice Chair of Research for the Department of Pediatrics. Dr. Delbert R. Wigfall, Associate Professor of Pediatrics, Associate Dean and Director of the Duke Institutional Multicultural Resource Center, will be our Minority Recruitment Advisor. The program will have two committees. The Internal Advisory Committee, chaired by Dr. Frank, is made up of members of our department and institution who are experienced investigators and mentors with leadership roles in our Institution. A subcommittee will assess and rank potential trainees. Recruitment of trainees from under-represented minorities will be a focus of our program. Dr. Frank will select the trainees. The Committee will interview the trainees and mentors on a regular basis. They, in concert with Drs. Frank and Anderson, will initiate any needed actions to support the progress of the trainees through the program. The External Advisory Board, made up of internationally recognized scientists and pediatricians from across the United States, will review on an annual basis the accomplishment of the program goals, the progress of the trainees and advise the Principal Investigator. Four trainees will be admitted the first year and four supported each year of the program. The training period will last from two to five years. The trainees' will dedicate over 75% of their time to the training program. The mentors will be selected based on their success in mentoring, the pediatric relevance of their research, leadership roles, and NIH funding. The trainees will be required to take courses in Responsible Conduct of Research, grant and manuscript writing, and core courses that include an Introduction to Statistics, Analysis of Genetic Data, and Molecular Genetics of Human Disease. The trainees will be required to give oral presentations to develop their communication skills. We are committed to recruiting these trainees to our department faculty. Our previous success in training and developing the scientific careers of junior investigators supports the long-term goal of this CHRCDA to develop successful academic pediatric scientists.