Metals in Medicine Gordon Research Conference

医学中的金属戈登研究会议

• 批准号: 6777591
• 负责人: NICHOLAS P FARRELL
• 金额: $ 0.53万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-21 至 2005-07-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6777591
• 关键词: health science research; medicine; meeting /conference /symposium; metalloenzyme; metalloproteins; metals; travel

DESCRIPTION (provided by applicant): Funds are requested to support travel of participants to the Metals in Medicine Gordon Research Conference (MIM-GRC) to be held in July 2002 and July 2004 at Colby-Sawyer College (New London, NH). This MIM-GRC is the first of its kind. It is a natural extension of the popular and prestigious Metals in Biology Gordon Research Conference (MIB-GRC), which meets annually in January in Ventura, CA. The purpose of the conference is four-fold: * to present state-of-the-art research on metal-containing systems of medical importance, * to identify emerging areas of research opportunity, * to increase communication between scientists in academia, government, and industry, and * to foster the formation of new collaborative research efforts in the field.The understanding of the role of metals in cell regulation, the complexities of metal metabolism, and the relationship of metalloenzymes to genetic and environmental disease has seen major advances in recent years. The success of cisplatin and its congeners suggests that metal complexes can also be developed as therapeutic agents. Experience in the development of imaging and radiation therapy agents demonstrates that metal complexes can be tailored to provide clinically useful pharmacokinetic properties. The topics to be emphasized for the first MIM-GRC conference are (1) the role of metal-generated radicals in health and disease; (2) metalloproteins in health and disease; (3) metalloproteins as drug targets; (4) transport of metals and metal complexes; (5) magnetic resonance imaging agents; (6) metal ions, metal complexes and malaria; (7) radioimaging agents; (8) vanadium and chromium in health and disease and (9) metal ion-nucleic acid interactions. By facilitating the many interdisciplinary interactions necessary for this field to flourish the conference will play a key role in encouraging new enterprises in biomedical research. To ensure the best possible mix of investigators and programs, it is important that the cost of participation is not a limiting factor to the attendance of invited speakers, discussion chairs and, especially, young and minority attendees. The modest sum requested to support the MIMGRC will enable the organizers to invite and attract participants in a topic that has impact on a wide cross-section of health sciences.

说明（由申请人提供）： 需要资金支持参加将于 2002 年 7 月和 2004 年 7 月在科尔比索耶学院（新罕布什尔州新伦敦）举行的戈登医学金属研究会议 (MIM-GRC) 的与会者的旅费。该 MIM-GRC 是同类产品中的第一个。它是广受欢迎且享有盛誉的戈登生物学金属研究会议 (MIB-GRC) 的自然延伸，该会议每年 1 月在加利福尼亚州文图拉举行。会议的目的有四个： * 展示具有医学重要性的含金属系统的最先进研究， * 确定新兴的研究机会领域， * 加强学术界、政府和工业界科学家之间的交流，以及 * 促进该领域新的合作研究工作的形成。 了解金属在细胞调节中的作用、金属代谢的复杂性以及金属酶与遗传和环境疾病的关系 近年来取得了重大进展。顺铂及其同系物的成功表明金属络合物也可以开发为治疗剂。成像和放射治疗剂开发的经验表明，可以定制金属络合物以提供临床上有用的药代动力学特性。首届MIM-GRC会议重点讨论的议题是（1）金属生成自由基在健康和疾病中的作用； (2) 健康和疾病中的金属蛋白； (3)以金属蛋白为药物靶点； (4)金属和金属络合物的运输； (5)磁共振成像剂； (6)金属离子、金属络合物与疟疾； (7)放射显像剂； （8）钒和铬在健康和疾病中的作用以及（9）金属离子-核酸相互作用。通过促进该领域蓬勃发展所需的许多跨学科互动，会议将在鼓励生物医学研究新企业方面发挥关键作用。为了确保研究人员和项目的最佳组合，参与成本不应成为受邀演讲者、讨论主席，尤其是年轻和少数族裔与会者出席的限制因素，这一点很重要。支持 MIMGRC 所需的微薄资金将使组织者能够邀请并吸引参与者参与一个对健康科学广泛领域产生影响的主题。