Core--Monoclonal antibody

核心--单克隆抗体

• 批准号: 7116675
• 负责人: ALEX L KOLODKIN
• 金额: $ 22.91万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7116675
• 关键词: biomedical facility; biotechnology; immunologic substance development /preparation; monoclonal antibody

The aim of the Monoclonal Antibody Core is to generate mouse and rat monoclonal antibodies against proteins studied by NINDS investigators at JHU SOM. Antibodies are central for the analysis of protein function, and ongoing studies by the Primary Center Investigators and other NINDS-funded investigators at the JHU SOM have been severely limited by the availability of reliable quantities of unique mono-specific antibodies. The monoclonal facility will develop new antibodies with enhanced selectivity, providing a much-needed resource to the Center's primary investigators and also other NINDS-funded scientists at JHU SOM. No such facility currently exists at JHU SOM.

单克隆抗体核心的目的是产生小鼠和大鼠针对JHU SOM的NINDS研究人员研究的蛋白质的单克隆抗体。抗体是蛋白质功能分析的核心，初级中心研究者和其他nind资助的JHU SOM研究者正在进行的研究受到可靠数量的独特单特异性抗体的严重限制。单克隆设施将开发具有更高选择性的新抗体，为该中心的主要研究人员和JHU SOM的其他nind资助的科学家提供急需的资源。JHU SOM目前没有这样的设施。