Quantitative and Computational Biology Graduate Program

定量和计算生物学研究生课程

• 批准号: 6937218
• 负责人: DAVID BOTSTEIN
• 金额: $ 26.93万
• 依托单位: PRINCETON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-18 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6937218
• 关键词: Quantitative; Computational; Biology; Graduate; Program

DESCRIPTION (provided by applicant): Support is requested for a new multi-disciplinary training program in genomics at Princeton University, aimed at educating genome scientists with the quantitative and computational tools likely to be required for the biology of the future. The genome training program will support students in Princeton's new Graduate Program in Quantitative and computational Biology (QCB), a joint undertaking between the new Lewis-Sigler Institute for Integrative Genomics and four Princeton departments (Computer Science, Ecology and Evolutionary Biology, Molecular Biology, and Physics) and administered by the Institute. Genomics trainees will be able to do their thesis research with any of 54 QCB faculty in 10 departments united by common interests in quantitative and computational biology. Five genomics training slots are requested for the first year, 10 for the second, and 15 for each year thereafter, so that a steady-state population of 15 genomics trainees can be supported. In addition to fulfilling the requirements of one of the participating departments, genomics trainees will do research in any of a wide array of functional genomics projects in bacteria, eukaryotic models and mammalian systems; computational projects ranging from basic bio-informatics and molecular evolution to high-throughput data visualization; systems biology projects ranging from microbial metabolism to systems neuroscience; biophysical projects from basic structural biology to the construction of novel proteins and regulatory switches; and theoretical projects ranging from basic dynamical modeling to trying to model signal transduction in epithelia or neurons. Trainees will have an individualized training plan administered by the Executive Committee of the QCB and a Genomics Committee; formal training will include new courses in genomics and genomic analysis, a seminar series, a student-run journal club, and other multi-disciplinary activities centered in the Institute. Trainees will have the opportunity to teach in an innovative new multidisciplinary introductory program for undergraduates at Princeton. Finally, trainees and eligible faculty will participate in a number of activities designed to recruit and teach individuals who are members of under-represented minorities, and to extend the genomics message to high school teachers.

描述(由申请者提供)：普林斯顿大学新的多学科基因组学培训计划请求支持，该计划旨在用未来生物学可能需要的定量和计算工具教育基因组科学家。基因组培训计划将支持普林斯顿大学新的定量和计算生物学研究生计划(QCB)的学生，该计划是由新的Lewis-Sigler集成基因组研究所和普林斯顿大学的四个系(计算机科学、生态学和进化生物学、分子生物学和物理学)联合开展的，并由该研究所管理。基因组学实习生将能够与10个系的54名QCB教员中的任何人一起进行论文研究，这些教员因对定量和计算生物学的共同兴趣而团结在一起。第一年需要5个基因组学培训名额，第二年10个，之后每年15个，这样就可以支持15名基因组学学员的稳定群体。除了满足其中一个参与系的要求外，基因组学学员还将研究细菌、真核模型和哺乳动物系统中广泛的功能基因组学项目；从基础生物信息学和分子进化到高通量数据可视化的计算项目；从微生物新陈代谢到系统神经科学的系统生物学项目；从基础结构生物学到构建新蛋白质和调控开关的生物物理项目；以及从基本动力学建模到尝试模拟上皮细胞或神经元中的信号转导的理论项目。受训者将有一个由QCB执行委员会和基因组学委员会管理的个性化培训计划；正式培训将包括基因组学和基因组分析方面的新课程、一系列研讨会、学生开办的期刊俱乐部，以及以研究所为中心的其他多学科活动。受训者将有机会在普林斯顿大学为本科生开设的创新的多学科入门课程中任教。最后，受训者和合格的教职员工将参加一系列活动，旨在招募和教授代表不足的少数族裔成员，并将基因组学信息传播给高中教师。