Quantitative and Computational Biology Graduate Program

定量和计算生物学研究生课程

• 批准号: 7272894
• 负责人: DAVID BOTSTEIN
• 金额: $ 40.39万
• 依托单位: PRINCETON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-18 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7272894
• 关键词: Computational Biology; programs

DESCRIPTION (provided by applicant): Support is requested for a new multi-disciplinary training program in genomics at Princeton University, aimed at educating genome scientists with the quantitative and computational tools likely to be required for the biology of the future. The genome training program will support students in Princeton's new Graduate Program in Quantitative and computational Biology (QCB), a joint undertaking between the new Lewis-Sigler Institute for Integrative Genomics and four Princeton departments (Computer Science, Ecology and Evolutionary Biology, Molecular Biology, and Physics) and administered by the Institute. Genomics trainees will be able to do their thesis research with any of 54 QCB faculty in 10 departments united by common interests in quantitative and computational biology. Five genomics training slots are requested for the first year, 10 for the second, and 15 for each year thereafter, so that a steady-state population of 15 genomics trainees can be supported. In addition to fulfilling the requirements of one of the participating departments, genomics trainees will do research in any of a wide array of functional genomics projects in bacteria, eukaryotic models and mammalian systems; computational projects ranging from basic bio-informatics and molecular evolution to high-throughput data visualization; systems biology projects ranging from microbial metabolism to systems neuroscience; biophysical projects from basic structural biology to the construction of novel proteins and regulatory switches; and theoretical projects ranging from basic dynamical modeling to trying to model signal transduction in epithelia or neurons. Trainees will have an individualized training plan administered by the Executive Committee of the QCB and a Genomics Committee; formal training will include new courses in genomics and genomic analysis, a seminar series, a student-run journal club, and other multi-disciplinary activities centered in the Institute. Trainees will have the opportunity to teach in an innovative new multidisciplinary introductory program for undergraduates at Princeton. Finally, trainees and eligible faculty will participate in a number of activities designed to recruit and teach individuals who are members of under-represented minorities, and to extend the genomics message to high school teachers.

描述（由申请人提供）：要求支持普林斯顿大学基因组学的一个新的多学科培训计划，旨在教育基因组科学家，掌握未来生物学可能需要的定量和计算工具。基因组培训计划将支持普林斯顿大学新的定量和计算生物学研究生课程（QCB）的学生，这是新的Lewis-Sigler综合基因组学研究所和普林斯顿大学四个系（计算机科学，生态学和进化生物学，分子生物学和物理学）之间的联合事业，并由该研究所管理。基因组学的学员将能够做他们的论文研究与任何54 QCB教师在10个部门的共同利益团结在定量和计算生物学。第一年要求提供5个基因组学培训名额，第二年10个名额，此后每年15个名额，以便能够支助15名基因组学受训人员的稳定人数。除了满足参与部门之一的要求，基因组学学员将在细菌，真核模型和哺乳动物系统的功能基因组学项目中进行研究;从基础生物信息学和分子进化到高通量数据可视化的计算项目;从微生物代谢到系统神经科学的系统生物学项目;生物物理项目，从基础结构生物学到新型蛋白质和调节开关的构建;以及理论项目，从基础动力学建模到试图建模上皮细胞或神经元中的信号转导。学员将有一个个性化的培训计划，由QCB的执行委员会和基因组学委员会管理;正式的培训将包括基因组学和基因组学分析的新课程，系列研讨会，学生运行的期刊俱乐部，以及其他以研究所为中心的多学科活动。学员将有机会在普林斯顿大学为本科生开设一个创新的多学科入门课程。最后，受训人员和符合条件的教师将参加一些活动，这些活动旨在招募和教授代表性不足的少数群体成员，并将基因组学信息推广到高中教师。